2010 Fiscal Year Final Research Report
Mechanisms on muscle atrophy by long-term bed rest with or without rehabilitation on in old age
Project/Area Number |
20500470
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Jikei University School of Medicine |
Principal Investigator |
YAMAUCHI Hideki Jikei University School of Medicine, 医学部, 講師 (60220224)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 加齢 / 安静臥床 / 筋萎縮 / 筋変性 / リハビリテーション / 速筋化 |
Research Abstract |
For establishment of effective exercise conditions to reduce muscle atrophy with shifts to the faster characteristics by the physical inactivity, we examined the effects of continuous exercise with low load and intermittent exercise with high load that carried out during bed rest in young, middle, and old age. As a result, in both fast- and slow-twitch muscle, the muscle atrophy by bed rest became remarkable, but shifts to the faster characteristics became less with aging. Inhibitory effects was similar between both exercise regimens in the slow-twitch muscle in all aging stages, but reduction effect on an muscle atrophy was higher with intermittent exercise with high load than continuous exercise with low load in the fast-twitch muscle.
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Research Products
(5 results)