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2010 Fiscal Year Final Research Report

Development of Molecular Sorter using Nanofluidic Device

Research Project

  • PDF
Project/Area Number 20510114
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Nanomaterials/Nanobioscience
Research InstitutionThe University of Tokyo

Principal Investigator

YAMAMOTO Takatoki  The University of Tokyo, 大学院・理工学研究科, 准教授 (20322688)

Co-Investigator(Renkei-kenkyūsha) NOJIMA Takahiko  北里大学, 一般教育部自然科学教育センター (00291930)
FUKUBA Tatsuhiro  東京大学, 生産技術研究所, 特任准教授 (80401272)
Project Period (FY) 2008 – 2010
Keywords1分子イメージング / ナノ計測
Research Abstract

This work is to develop a single-molecule sensing device using nanofluidic system, which has a channel having tens to hundreds nanometer sized width and height. As results, we have successfully demonstrated the single DNA molecule detection in the nanochannel by ultra-sensitive (fA order) electric measurement. Furthermore, we have also successfully demonstrated an on-chip electric measurement circuit, which was integrated on the nanofluidic chip to realize portable system.

  • Research Products

    (12 results)

All 2011 2010 2009 2008

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (8 results)

  • [Journal Article] マイクロ\ナノ流体デバイスのナノバイオ応用2011

    • Author(s)
      山本貴富喜
    • Journal Title

      機械の研究 Vol.63, No.2

      Pages: 117-124

    • Peer Reviewed
  • [Journal Article] Nanofluidic Single-molecule Sorting of DNA : A New Concept in Separation and Analysis of Biomolecul2010

    • Author(s)
      Takatoki Yamamoto, Teruo Fujii
    • Journal Title

      Nanotechnology Vol.21, No.39

      Pages: 395502

    • Peer Reviewed
  • [Journal Article] Nonlinear Electrical Impedance Measurement Controlling Conformation of DNA2010

    • Author(s)
      Takatoki Yamamoto, Sang-Wook Lee, Teruo Fujii
    • Journal Title

      Journal of Robotics and Mechatronics Vol.22, No.5

      Pages: 601-607

    • Peer Reviewed
  • [Journal Article] シリコーンゴム製マイクロ流体デバイスのライフサイエンス応用2010

    • Author(s)
      山本貴富喜
    • Journal Title

      材料の科学と工学 Vol.47 No.5

      Pages: 6-11

    • Peer Reviewed
  • [Presentation] Direct bonding of solid-state silicone by atmospheric-pressure surface excitation2010

    • Author(s)
      Wataru Okada, Takatoki Yamamoto
    • Organizer
      The 27th Sensor Symposium on Sensors, Micromachines and Applied Systems 117
    • Place of Presentation
      Shimane
    • Year and Date
      20101014-20101015
  • [Presentation] 両親媒性マクロ構造体による自己組織化の研究2010

    • Author(s)
      山腰一平, 山本貴富喜
    • Organizer
      第2回マイクロナノ工学シンポジウム, 講演論文集 185-186
    • Place of Presentation
      島根
    • Year and Date
      20101013-20101015
  • [Presentation] 電気的1分子検出のためのナノ流体デバイスの研究2010

    • Author(s)
      淵上裕次郎, 山本貴富喜
    • Organizer
      第2回マイクロナノ工学シンポジウム, 講演論文集 15-16
    • Place of Presentation
      島根
    • Year and Date
      20101013-20101015
  • [Presentation] NANOFLUIDIC SINGLE-MOLECULE SORTER CONCEPTUALLY PROVEN BY SORTING OF DNA2010

    • Author(s)
      T.Yamamoto, T.Fujii
    • Organizer
      The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS2010) 1874-1876
    • Place of Presentation
      Groningen, The Netherland
    • Year and Date
      20101003-20101007
  • [Presentation] Multiphysics simulation to design micro/nanofluidic device for biotechnology applications2010

    • Author(s)
      Takatoki Yamamoto
    • Organizer
      COMSOL conference of Tokyo 2010
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-12-03
  • [Presentation] マイクロ・ナノ流体デバイスのライフサイエンス応用2010

    • Author(s)
      山本貴富喜
    • Organizer
      日本機械学会,実験流体力学-マイクロ流れ実験の基礎と応用-
    • Place of Presentation
      東京
    • Year and Date
      2010-08-24
  • [Presentation] Design using COMSOL for life science application of microfabrication technology2009

    • Author(s)
      Takatoki Yamamoto, Teruo Fujii
    • Organizer
      COMSOL conference of Tokyo 2009
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-12-04
  • [Presentation] 機械学会No.08-59講習会-実験流体力学-マイクロ流れ実験の基礎と応用-2008

    • Author(s)
      山本貴富喜
    • Organizer
      日本機械学会
    • Place of Presentation
      東京
    • Year and Date
      2008-08-26

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Published: 2012-01-26   Modified: 2016-04-21  

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