2010 Fiscal Year Final Research Report
The development of novel bioactive compounds from the nematocysts.
| Project/Area Number |
20510197
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Living organism molecular science
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| Research Institution | Tokyo University of Marine Science and Technology |
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Principal Investigator |
NAGAI Hiroshi Tokyo University of Marine Science and Technology, 海洋科学部, 教授 (50291026)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生物活性物質 / 海洋天然物化学 |
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| Research Abstract |
The screening of the novel bioactive compounds were accomplished on some cnidarians and isolated nematocysts. We have succeeded in the isolation and characterization of some new bioactive proteins and small molecular weight compounds. A new actinoporin toxin was isolated and characterized from the sea anemone Anthopleura asiatica. Furthermore, a new Kunitz type protease inhibitor protein was characterized from the sea anemone Phyllodiscus semoni.
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