2010 Fiscal Year Final Research Report
Development of novel sulfur-atom donating agents intended to thiiranate alkenes
| Project/Area Number |
20550032
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Saitama University |
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Principal Investigator |
YOSHIAKI Sugihara Saitama University, 理工学研究科, 准教授 (00272279)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 硫黄原子導入 / 三員環化合物 / アルケン / チイラン / チイラン化 / 電子吸引性基 / 脱離基 / 塩化スルファニル |
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| Research Abstract |
Sulfur-atom donating reagents taking advantage of both the electron withdrawing character and the leaving group ability of the substituents bonding directly with the sulfur atom were easily synthesized from inorganic or organic sulfur compounds. As a result of investigating their sulfuration ability, some reagents were found to thiiranate alkenes with retention of configuration. The reagent synthesized from artificial sweetener saccharin was able to sulfurate benzothiophene, one of the electron-rich heteroaromatic compo unds, under mild reaction conditions.
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[Remarks] 杉原儀昭,新規なアルケンのチイラン化法の開発,産総研-大学連携セミナー,平成22 年7 月26 日,産業技術総合研究所(茨城県つくば市)
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[Remarks] 杉原儀昭,アルケンを出発物質とするチイランの一段階合成法の開発,第167回化学コースコロキウム,平成23年1月13日,首都大学東京理工学研究科分子物質化学専攻(東京都八王子市)
