2010 Fiscal Year Final Research Report
Development of novel chiral bronsted acid catalyst based on intramolecular hydrogen bonding
| Project/Area Number |
20550045
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
TAKAGI Ryukichi Hiroshima University, 大学院・理学研究科, 助教 (90304394)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 合成有機化学 / 有機分子触媒 / 不斉反応 / 水素結合 / Diels-Alder反応 |
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| Research Abstract |
A novel chiral bronsted acid catalyst based on intramolecular hydrogen bonding have been developed. The novel chiral bronsted acid slightly accelerated the Diels-Alder reaction of cross-conjugated dienone and cyclopentadiene than the original one. ONIOM calculations suggested that the chiral bronsted acid interact with the dienone by double hydrogen bond in the Diels-Alder reaction.
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