2010 Fiscal Year Final Research Report
Synthesis of expanded poly(α-amino acid)s having metal complex skeleton and construction of secondary structures
| Project/Area Number |
20550063
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Inorganic chemistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
OKAMURA Taka-aki Osaka University, 大学院・理学研究科, 講師 (90252569)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 超分子化学 / 金属錯体 / ペプチド / 非天然型アミノ酸 |
|---|
| Research Abstract |
A series of expanded poly(α-amino acid)s containing metal complexes was designed and synthesized. The molecular structures in solution and the crystal structures were determined. The conformation of the polymer depends finely on the component amino acids. Slight changes of the side chain of amino acid residues resulted in varieties of conformations, e.g., helical and zigzag structures. A suitable select of linkage could alter the handedness of the helix.
|
