2010 Fiscal Year Final Research Report
Development of three-dimensional polylactic acid-piezoelectric material scaffold
| Project/Area Number |
20560091
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Doshisha University |
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Principal Investigator |
KATAYAMA Tsutao Doshisha University, 生命医科学部, 教授 (70161065)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMACHI Eiji 同志社大学, 生命医科学部, 教授 (60099893)
TANAKA Kazuto 同志社大学, 生命医科学部, 准教授 (50303855)
MORITA Yusuke 同志社大学, 生命医科学部, 准教授 (80368141)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生体材料 / 圧電材料 / 足場材料 / 骨髄細胞 / 骨分化 |
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| Research Abstract |
A cultivation system was designed to evaluate piezoelectric effects of the BaTiO_3 (BTO) ceramics on bone marrow cells, and rat bone marrow cells seeded on surfaces of the BTO ceramics were cultured in culture medium. ALP activity on the charged BTO surface was slightly higher than that on the non-charged BTO surface. The amount of calcium on the charged BTO surface was also higher than that on the non-charged BTO surface. These results showed that the electric charged BTO surface enhanced osteogenic differentiation.
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Research Products
(8 results)
