2010 Fiscal Year Final Research Report
Effects of the mechanical relationships between collagen fibrils and ground substances on the mechanical adaptation of biological tissues
| Project/Area Number |
20560092
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
YAMAMOTO Noritaka Ritsumeikan University, 理工学部, 教授 (40210546)
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| Project Period (FY) |
2008 – 2010
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| Keywords | バイオメカニクス / 力学的性質 / 微細構造 / 力学的適応 / 腱 / コラーゲン / 原線維 / 線維間物質 |
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| Research Abstract |
Tendons and ligaments have such hierarchical structures as collagen fascicles, fibers, and fibrils. The fascicles consist of fibers and fibrils embedded in ground substances such as proteoglycans. In this study, these specimens were stretched to failure and their microstructure was observed with electron microscope and atomic force microscope. I elucidated the mechanical relationships among the fascicles, fibrils, and proteoglycans.
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