2010 Fiscal Year Final Research Report
Regulation of odorant receptor gene expression
| Project/Area Number |
20570208
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
HIROTA Junji Tokyo Institute of Technology, バイオ研究基盤支援総合センター, 准教授 (60405339)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 遺伝子発現調節 / 嗅覚受容体多重遺伝子 |
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| Research Abstract |
To study molecular mechanisms underlying odorant receptor (OR) gene expression in mice, we have screened transcription factors which might be involved in OR gene regulation, and have made transgenic mice to identify promoter/enhancer regions. We found a few candidate factors which may regulate OR gene expression. In addition, we have constructed transgenes to identify regulatory regions OR genes, and have obtained several transgenic lines.
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