2010 Fiscal Year Final Research Report
Molecular mechanisms of the maintenance of sterol homeostasis in yeast
Project/Area Number |
20580072
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied microbiology
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Research Institution | The University of Tokyo |
Principal Investigator |
FUKUDA Ryouichi 東京大学, 大学院・農学生命科学研究科, 助教 (50323481)
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Project Period (FY) |
2008 – 2010
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Keywords | 酵母 / ステロール / 脂質 / 輸送 |
Research Abstract |
We constructed a system, in which the transport of sterol from the plasma membrane to the ER is evaluated in vitro using budding yeast Saccharomyces cerevisiae, and analyzed its mechanism. We also construct systems to assay the sterol transport from the ER to the vacuole or mitochondria in yeast.
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