2010 Fiscal Year Final Research Report
Elucidation of control mechanism of spore germination in microorganisms by self-germination inhibitors of actinomycetes.
| Project/Area Number |
20580109
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
NATSUME Masahiro Tokyo University of Agriculture and Technology, 大学院・農学研究院, 教授 (10201683)
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| Project Period (FY) |
2008 – 2010
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| Keywords | Streptomyces coelicolor / Streptomyces griseus / Streptomyces viridochromogenes / germicidin / hypnosin / 放線菌 / 発芽抑制物質 |
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| Research Abstract |
Four germicidins were isolated from Streptomyces coelicolor. Their germination inhibitory activity and contents in spores revealed that germicidins function as self-germination inhibitors. Reexamination in S. viridochromogenes indicated that the major self-germination inhibitor was found to be an EtOAc-soluble neutral substance. The similar inhibitor was also produced by S.griseus.
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