2010 Fiscal Year Final Research Report
NADPH oxidase targeted metabolic syndrome prevention
| Project/Area Number |
20580137
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YAMASAKI Masao 宮崎大学, 農学部, 准教授 (80381060)
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| Project Period (FY) |
2008 – 2010
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| Keywords | NADPHオキシダーゼ / メタボリックシンドローム / インテグリンβ1 / がん |
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| Research Abstract |
Recent studies have shown that reactive oxygen species generated by NADPH oxidase are causative agents of metabolic syndrome. In order to elucidate the effects of NADPH oxidase inhibitors and antioxidants on metabolic syndrome prevention, the effects of NADPH oxidase inhibitors and an antioxidant on the expression level of integrin. 1, a metabolic syndrome related protein, was investigated. Both NADPH oxidase inhibitors and an antioxidant decreased the expression level of integrin. 1, suggesting that NADPH oxidase inhibitors and antioxidants are promising candidates for metabolic syndrome prevention.
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[Journal Article] Effect of Highly Lipolyzed Goat Cheese on HL-60 Human Leukemia Cells : Antiproliferative Activity and Induction of Apoptotic DNA Damage
Author(s)
Yasuda, S., Kuwata, H., Kawamoto, K., Shirakawa, J., Atobe, S., Hoshi, Y., Yamasaki, M., Nishiyama, K
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Journal Title
Peer Reviewed
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