2010 Fiscal Year Final Research Report
Degradation and detoxification of pharmaceuticals and personal care products by white rot fungi and their ligninolytic enzymes
| Project/Area Number |
20580173
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Wood science
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| Research Institution | Shizuoka University |
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Principal Investigator |
NISHIDA Tomoaki Shizuoka University, 農学部, 教授 (10252165)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAI Shingo 静岡大学, 農学部, 教授 (70192549)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 白色腐朽菌 / リグニン分解酵素 / 医薬品 / 身体ケア製品 |
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| Research Abstract |
In this study, we demonstrated that white rot fungi and their ligninolytic enzymes are effective in degrading and detoxifying pharmaceuticals and personal care products, such as butylparabens (preservatives), diclofenac and mefenamic acid (antiinflammatory drugs), and triclosan (antimicrobial agent). Furthermore, it was confirmed that ligninolytic enzymes are also effective in degrading carbamazepine (antiepileptic drug) which is highly persistent and removed by less than 10% after conventional wastewater treatment.
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