Sexual plasticity of fish gonad

2010 Fiscal Year Final Research Report

• Project/Area Number: 20580214
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General fisheries
• Research Institution: Teikyo University of Science & Technology
• Principal Investigator: HIRAI Toshiaki 帝京科学大学, 生命環境学部, 准教授 (30238331)
• Project Period (FY): 2008 – 2010
• Keywords: 生殖腺 / 性分化 / 可塑性 / 水産学 / 発生・分化

Research Abstract

Sexual plasticity of fish gonad was addressed by morphologial and molecular biological approaches. In mauring ovary of common carp, special regions retain a potential to be differentiated into testicular tissue. Gonadal soma derived growth factor(GSDF) is expressed in the regions, suggesting its involvement in the sexual plasticity. This growth factor is shown to exert a crucial role in the protogynous sex change(from ovary to testis) in wrasse. Meanwhile, estrogen administration to genetic male of common carp showed that sexual plasticity regressed as testicular tissue architecture was formed.

Research Products

• [Journal Article] (2011)
  • Author(s): Kitano, H., Irie, S., Ohta, K., Hirai, T., Yamaguchi, A. and Matsuyama, M.
  • Journal Title: Gen. Comp. Endocr Volume: 172 Pages: 268-276
  • Peer Reviewed
• [Journal Article] (2010)
  • Author(s): Hayashi, Y., Kobira, H., Yamaguchi, T., Shiraishi, E., Yazawa, T., Hirai, T., Kamei, Y. and Kitano, T.
  • Journal Title: Mol. Reprod. Dev Volume: 77 Pages: 679-686
  • Peer Reviewed
• [Journal Article] (2010)
  • Author(s): Alam, M. A., Kobayashi, Y., Hirai, T. and Nakamura, M.
  • Journal Title: Comp. Biochem. Physiol. A Volume: 156 Pages: 364-371
  • Peer Reviewed
• [Journal Article] (2009)
  • Author(s): Mittelholzer, C., Andersson, E., Consten, D., Taranger, G. L., Hirai, T., Senthilkumaran, B., Nagahama, Y. and Norberg, B.
  • Journal Title: Gen. Comp. Endocrinol Volume: 160 Pages: 47-58
  • Peer Reviewed
• [Journal Article] (2008)
  • Author(s): Alam, M. A., Kobayashi, Y., Horiguchi, R., Hirai, T. and Nakamura, M.
  • Journal Title: Gen. Comp. Endocrinol Volume: 157 Pages: 75-85
  • Peer Reviewed
• [Journal Article] (2008)
  • Author(s): Ogawa, S., Akiyoshi, M., Higuchi, M., Nakamura, M. and Hirai, T.
  • Journal Title: CYBIUM International Journal of Ichthyology Volume: 32 Pages: 102-103
  • Peer Reviewed
• [Presentation] Analysis of regulational mechanism of follicle-stimulating hormone receptor(FSHR) expression using FSHR-GFP transgenic medaka (2011)
  • Author(s): T. Uchikawa, H. Kobira, T. Hirai and T. Kitano
  • Organizer: 9th International Symposium on Reproductive Physiology of Fish
  • Place of Presentation: Cochin, India
  • Year and Date: 20110800
• [Presentation] Molecular cloning ofcommon carp gonadal soma derived growth factor(GSDF) (2011)
  • Author(s): T. Fujimoto, T. Ohmae, S. Sato, R. Horiguchi, Y. Nagahama and T. Hirai
  • Organizer: 9th International Symposium on Reproductive Physiology of Fish
  • Place of Presentation: Cochin, India
  • Year and Date: 20110800
• [Presentation] コイ(Cyprinus carpio)生殖腺体細胞由来増殖因子(GSDF)のcDNAクローニング (2010)
  • Author(s): 藤本孝史、大前貴俊、平井俊朗
  • Organizer: 第35回日本比較内分泌学会大会
  • Place of Presentation: 静岡
  • Year and Date: 20101100
• [Presentation] Regulational mechanism of follicle-stimulating hormone receptor expression in medaka(Oryzias latipes) (2010)
  • Author(s): T. Uchikawa, H. Kobira, T. Hirai and T. Kitano
  • Organizer: 第43回日本発生生物学会大会
  • Place of Presentation: 京都
  • Year and Date: 20100600
• [Presentation] メダカの温度依存性性決定におけるコルチゾルの関与 (2010)
  • Author(s): 林裕輝、小平博史、山口寿哉、白石絵吏、平井俊朗、北野健
  • Organizer: 平成22年度日本水産学会大会
  • Place of Presentation: 藤沢
  • Year and Date: 20100300
• [Presentation] メダカ濾胞刺激ホルモン受容体の発現制御機構の解析 (2009)
  • Author(s): 小平博史、平井俊朗、北野健
  • Organizer: 第34回日本比較内分泌学会大会
  • Place of Presentation: 大阪
  • Year and Date: 20091200
• [Presentation] Functional analyses of follicle-stimulating hormone(FSH) and FSH-receptor in early gonadal differentiation in medaka(Oryzias latipes) (2009)
  • Author(s): H. Kataura, H. Ichimaru, E. Shiraishi, A. Kanamori, T. Hirai and T. Kitano
  • Organizer: 16th International Congress of Comparative Endocrinology
  • Place of Presentation: 香港
  • Year and Date: 20090600
• [Presentation] Sexual Plasticity in the gonads of common carp(Cyprinus carpio) (2009)
  • Author(s): S. Ogawa, M. Higuchi, S. Sato, M. Nakamura and T. Hirai
  • Organizer: 16th International Congress of Comparative Endocrinology
  • Place of Presentation: 香港
  • Year and Date: 20090600
• [Presentation] Functional analysis of follicle-stimulating hormone using sycp1-GFP/olvas-DsRED double transgenic medaka line(Oryzias latipes) (2009)
  • Author(s): H. Kataura, H. Ichimaru, E. Shiraishi, A. Kanamori, T. Hirai, and K. Kitano
  • Organizer: 第42回日本発生生物学会大会
  • Place of Presentation: 新潟
  • Year and Date: 20090500
• [Presentation] コイ雄生殖腺の性的可塑性についての研究成長と性分化の関連性平 (2009)
  • Author(s): 小川智史、小松加苗、樋口正仁、中村將、平井俊朗
  • Organizer: 平成21年度日本水産学会春季大会
  • Place of Presentation: 東京
  • Year and Date: 20090300
• [Presentation] コイ雌生殖腺の性的可塑性卵巣内における精子形成の誘導 (2008)
  • Author(s): 小川智史、樋口正仁、中村將、平井俊朗
  • Organizer: 第33回日本比較内分泌学会大会
  • Place of Presentation: 広島
  • Year and Date: 20081200
• [Presentation] Sexual Plasticity in the ovary of common carp(Cyprinus carpio) (2008)
  • Author(s): S. Ogawa, M. Akiyoshi, M. Higuchi, M. Nakamura and T. Hirai
  • Organizer: International Symposium on Sex Determination and Gametogenesis in Fish : Current Status and Future Directions
  • Place of Presentation: Hawaii, USA
  • Year and Date: 20080500