2011 Fiscal Year Final Research Report
Temperature adaptation and regulatory mechanisms of molluscan muscle contraction
| Project/Area Number |
20580217
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fisheries chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
TANAKA Hiroyuki 北海道大学, 大学院・水産科学研究院, 助教 (90241372)
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| Co-Investigator(Kenkyū-buntansha) |
OJIMA Takao 北海道大学, 大学院・水産科学研究院, 教授 (30160865)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 軟体動物 / 筋収縮調節 / 分子機構 / トロポニン / 遺伝子 / 温度適応 |
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| Research Abstract |
We revealed that molluscan troponin-tropomyosin, the regulatory protein of muscle contraction, functions through the novel molecular mechanism that is different from those known for vertebrate troponin-tropomyosin. In addition, we suggested that the novel mechanism is present in arthropods and echinoderms and ubiquitous for invertebrate animals. Furthermore, we revealed that molluscs express various isoforms of the regulatory proteins, the biochemical properties of which are significantly different from each other. We proposed that the presence of these isoforms should be associated with the temperature adaptation of the molluscs and the difference of the locomotor habits of molluscan species.
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