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2011 Fiscal Year Final Research Report

Temperature adaptation and regulatory mechanisms of molluscan muscle contraction

Research Project

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Project/Area Number 20580217
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Fisheries chemistry
Research InstitutionHokkaido University

Principal Investigator

TANAKA Hiroyuki  北海道大学, 大学院・水産科学研究院, 助教 (90241372)

Co-Investigator(Kenkyū-buntansha) OJIMA Takao  北海道大学, 大学院・水産科学研究院, 教授 (30160865)
Project Period (FY) 2008 – 2011
Keywords軟体動物 / 筋収縮調節 / 分子機構 / トロポニン / 遺伝子 / 温度適応
Research Abstract

We revealed that molluscan troponin-tropomyosin, the regulatory protein of muscle contraction, functions through the novel molecular mechanism that is different from those known for vertebrate troponin-tropomyosin. In addition, we suggested that the novel mechanism is present in arthropods and echinoderms and ubiquitous for invertebrate animals. Furthermore, we revealed that molluscs express various isoforms of the regulatory proteins, the biochemical properties of which are significantly different from each other. We proposed that the presence of these isoforms should be associated with the temperature adaptation of the molluscs and the difference of the locomotor habits of molluscan species.

  • Research Products

    (3 results)

All 2012 2009

All Presentation (3 results)

  • [Presentation] ロブスター・トロポニンCのNおよびC末端ドメインへのCa^<2+>結合が筋収縮調節において果たす役割2012

    • Author(s)
      田中啓之
    • Organizer
      2012年生体運動研究合同班会議
    • Place of Presentation
      筑波大学
    • Year and Date
      2012-01-06
  • [Presentation] 軟体動物および脊椎動物トロポニンのサブユニット間相互作用の比較2009

    • Author(s)
      塚本洋之
    • Organizer
      日本水産学会秋季大会
    • Place of Presentation
      岩手県民情報交流センター
    • Year and Date
      2009-10-01
  • [Presentation] 節足動物トロポニンCの構造と機能に関する研究2009

    • Author(s)
      高橋博貴
    • Organizer
      日本水産学会秋季大会
    • Place of Presentation
      岩手県民情報交流センター
    • Year and Date
      2009-10-01

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Published: 2013-07-31  

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