2010 Fiscal Year Final Research Report
Search and the functional analysis of lipophilic signaling molecule as a regulator of adipogenesis in the ruminants.
| Project/Area Number |
20580304
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Shinshu University |
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Principal Investigator |
SASAKI Shin-ichi Shinshu University, 農学部, 教授 (00003682)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 反芻動物 / 脂肪細胞分化制御 / シグナル伝達 / 生理活性物質 / 核内転写因子 |
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| Research Abstract |
To date, the regulating mechanism of adipogenesis in the ruminants have not been clear. Therefore, we investigated the search and the functional analysis of lipophilic signaling molecule as a regulator of adipogenesis in the ruminants. In this study we demonstrated that VFA and lactoseureid are an intrinsic and an extrinsic factor, respectively, controlling the gene expression of PPAR γ-2 and LXRα in the ruminants, and VFA is a prominannt inducer and regulator on the ruminant adipocyte differentiation.
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Research Products
(6 results)
