2010 Fiscal Year Final Research Report
Development of determination method of absolute configuration of natural products based on induced exciton coupling, computed by quantum chemical calculation
| Project/Area Number |
20590030
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyushu University of Health and Welfare |
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Principal Investigator |
HOSOI Shinzo Kyushu University of Health and Welfare, 薬学部, 准教授 (60209236)
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| Co-Investigator(Kenkyū-buntansha) |
KATSUMOTO Yukiteru 広島大学, 大学院・理学研究科, 助教 (90351741)
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| Co-Investigator(Renkei-kenkyūsha) |
TANAKA Takeyuki 愛媛大学, 学内共同利用施設, 研究員 (50332763)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 絶対配置決定 / 円二色性 / 量子化学計算 / 立体配座解析 / カロテノイド |
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| Research Abstract |
A straightforward strategy for chiral discrimination in a specified carotenoid, β-isocryptoxanthin using a CD band, which is insensitive to conformational changes, computed by quantum chemical calculation is reported. This protocol may be applicable to estimating the absolute configuration of a number of natural carotenoids.
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