2010 Fiscal Year Final Research Report
Construction of influenza virosome and its development to preparation of vaccine
| Project/Area Number |
20590033
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | University of Toyama |
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Principal Investigator |
UENO Masaharu University of Toyama, 大学院・医学薬学研究部(薬学), 教授 (40080197)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 製剤学 |
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| Research Abstract |
Influenza is one of the common infectious diseases caused by influenza virus. Vaccines are the most effective means to fight infectious diseases. Liposomes are known to be effective immunoadjuvants. In this article, we introduced a new method to prepare the liposome vaccine, "influenza virosomes", using inter-membrane protein transfer. We concluded that this method is useful to prepare virosomes. The virosomes showed high immunoactivity especially with MDP derivatives.
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Research Products
(5 results)
