The use of stable isotopic compositions for cannabis comparison

2010 Fiscal Year Final Research Report

• Project/Area Number: 20590051
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Physical pharmacy
• Research Institution: National Research Institute of Police Science
• Principal Investigator: IWATA Yuko 科学警察研究所, 法科学第三部, 主任研究官 (20356190)
• Project Period (FY): 2008 – 2010
• Keywords: 分析化学 / ガスクロマトグラフィー / 安定同位体比質量分析

Research Abstract

We developed an analytical procedure using gas chromatograph-isotope ratio mass spectrometer which allows acquisition of compound specific stable-isotopic compositions of herbal cannabis, marijuana, and evaluated the stable-isotopic compositions for distinguishing or linking marijuana samples. The sets of marijuana samples from different origin were able to discriminate using stable-isotopic compositions of the principal constituents of cannabis.

Research Products

• [Journal Article] Seized methamphetamine samples with unique profiles of stable nitrogen isotopic composition documented by stable isotope ratio mass spectrometry (2010)
  • Author(s): Iwata, Y. T., Kuwayama, K., Tsujikawa, K., Miyaguchi, H., Kanamori, T., Inoue, H.
  • Journal Title: Forensic Toxicology Volume: 28 Pages: 119-123
  • Peer Reviewed
• [Journal Article] Evaluation method for linking methamphetamine seizures using stable carbon and nitrogen isotopic compositions : A complementary study with impurity profiling (2008)
  • Author(s): Iwata, Y. T., Kuwayama, K., Tsujikawa, K., Miyaguchi, H., Kanamori, T., Inoue, H.
  • Journal Title: Rapid Communications in Mass Spectrometry Volume: 22 Pages: 3816-3822
  • Peer Reviewed
• [Presentation] The Use of Isotope Ratio Mass Spectrometry for Drug Profiling (2011)
  • Author(s): Iwata, Y. T., Inoue, H.
  • Organizer: IUPAC international congress for analytical sciences 2011(ICAS 2011)
  • Place of Presentation: 京都府京都市
  • Year and Date: 2011-05-25
• [Presentation] The use of gas chromatographic isotope ratio mass spectrometry for cannabis profiling (2010)
  • Author(s): Iwata, Y. T., Inoue, H., Kuwayama, K., Tsujikawa, K., Miyaguchi, H., Kanamori T., Fukushima, H.
  • Organizer: 48th Annual Meeting of the International Association of Forensic Toxicologists
  • Place of Presentation: Bonn, Germany
  • Year and Date: 2010-09-02
• [Presentation] 安定同位体比分析による大麻の異同識別 (2010)
  • Author(s): 岩田祐子,三熊敏靖,桑山健次,辻川健治,宮口一,金森達之,井上博之
  • Organizer: 日本法中毒学会第29年会
  • Place of Presentation: 東京都文京区
  • Year and Date: 2010-05-24
• [Presentation] Evaluation method for linking drug seizures using stable carbon and nitrogen isotopic compositions : A complementary study with impurity profiling (2009)
  • Author(s): Iwata, Y. T., Inoue, H., Kuwayama, K., Tsujikawa, K., Miyaguchi, H., Kanamori T., Fukushima, H.
  • Organizer: 47th International Meeting-The International Association of Forensic Toxicologists
  • Place of Presentation: Geneva, Switzerland
  • Year and Date: 2009-08-27
• [Presentation] 安定同位体比分析による薬物プロファイリング (2009)
  • Author(s): 岩田祐子、井上博之
  • Organizer: 第57回質量分析総合討論会
  • Place of Presentation: 大阪府大阪市
  • Year and Date: 2009-05-14
• [Presentation] 安定同位体比分析によるメタンフェタミンの異同識別 (2008)
  • Author(s): 岩田祐子,桑山健次,辻川健治,宮口一,金森達之,井上博之
  • Organizer: 日本法科学技術学会第14回学術集会
  • Place of Presentation: 東京都港区
  • Year and Date: 2008-11-07