2010 Fiscal Year Final Research Report
Discovery of the new anti-cancer drug candidates from Okinawan subtropical plants.
| Project/Area Number |
20590103
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Drug development chemistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
MATSUNAMI Katsuyoshi Hiroshima University, 大学院・医歯薬学総合研究科, 准教授 (70379890)
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| Co-Investigator(Kenkyū-buntansha) |
OTSUKA Hideaki 広島大学, 大学院・医歯薬学総合研究科, 教授 (00107385)
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| Co-Investigator(Renkei-kenkyūsha) |
TAHARA Hidetoshi 広島大学, 大学院・医歯薬学総合研究科, 教授 (00271065)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生物活性物質 |
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| Research Abstract |
Several biologically active compounds were isolated from the Okinawan subtropical plants. These compounds could inhibit the tumor cell growth and/or inhibit the multidrug resistance activity of cultured cell, which are clinically important features for cancer chemotherapy. The absolute structures of the isolated compounds were elucidated by spectroscopic and chemical modification analysis. The results were published in international scientific journals.
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