2010 Fiscal Year Final Research Report
Molecular mechanism of pituitary cell degeneration in a fatigued animal model.
Project/Area Number |
20590194
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
General anatomy (including Histology/Embryology)
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Research Institution | Osaka City University |
Principal Investigator |
OGAWA Tokiko Osaka City University, 大学院・医学研究科, 特任助教 (30382229)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 持続的ストレス / 下垂体 / 細胞死 / 細胞増殖 |
Research Abstract |
Cellular dysfunctions were observed in two types of pituitary cells of a fatigued rat model. One was melanotorophs cell death induced by abnormality of hypothalamic neurons, and the other was proliferating disorder of somatotrophs. As a result of molecular analysis, part of the mechanism inducing cellular dysfunctions were founded.
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Research Products
(17 results)