2010 Fiscal Year Final Research Report
Analysis of bi-directional signal transduction elicited by adhesion between leukocyte and endothelial cells
| Project/Area Number |
20590214
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
General physiology
|
|---|
| Research Institution | Osaka City University |
|---|
Principal Investigator |
FUJITA Hisakazu Osaka City University, 大学院・医学研究科, 講師 (30212187)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KATO Takayuki 大阪市立大学, 大学院・医学研究科, 講師 (50343413)
KITAGAWA Seiichi 大阪市立大学, 大学院・医学研究科, 教授 (50133278)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 細胞間接着 / カルパイン |
|---|
| Research Abstract |
1)We found the molecular interaction between JAML (Junctional adhesion molecule-like) and ESAM (Endothelial cell-selective adhesion molecule). 2) Potent calpain inhibitors stimulate cell functions via activation of human formyl peptide receptor and human formyl peptide receptor-like 1.
|
Research Products
(8 results)
