2010 Fiscal Year Final Research Report
Role of the orexin neurons in body temperature regulation
| Project/Area Number |
20590226
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Kagoshima University |
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Principal Investigator |
KUWAKI Tomoyuki Kagoshima University, 医歯学総合研究科, 教授 (80205260)
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| Research Collaborator |
ZHANG Wei 千葉大学, 医学研究院, 特任研究員
SUNANAGA Jinko 鹿児島大学, 医歯学総合研究科, 大学院生
TAKAHASHI Yoshiko 鹿児島大学, 医歯学総合研究科, 大学院生
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| Project Period (FY) |
2008 – 2010
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| Keywords | オレキシン / 視床下部 / 体温調節 / ストレス |
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| Research Abstract |
Possible role of orexin (hypocretin), a hypothalamic neuropeptide, in body temperature regulation was investigated using genetically engineered mice. Orexin containing neurons are indispensable for tress-induced thermogenesis although they minimally contribute to basal body temperature. Surprisingly, not orexin but co-transmitters contained in the orexin neurons are important for stress-induced thermogenesis.
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Research Products
(36 results)
