2011 Fiscal Year Final Research Report
The regulation of actin assembly during myofibrillogenesis
| Project/Area Number |
20590285
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General medical chemistry
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| Research Institution | Kyushu University |
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Principal Investigator |
TAKEYA Ryu 九州大学, 医学研究院, 講師 (50335981)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 細胞医化学 |
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| Research Abstract |
In striated muscle, this actin filaments and thick filaments of myosin are highly organized to form myofibrils. However, little is known about the mechanism for organization of actin filaments in the contractile unit sarcomere. In the present study, we show that the mammalian formin Fhod3 regulates actin assembly and sarcomere organization in striated muscles.
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Research Products
(13 results)
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[Journal Article] Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival.2008
Author(s)
Shono T, Yokoyama N, Uesaka T, Kuroda J, Takeya R, Yamasaki T, Amano T, Mizoguchi M, Suzuki SO, Niiro H, Miyamoto K, Akashi K, Iwaki T, Sumimoto H, Sasaki T.
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Journal Title
Int. J. Cancer
Volume: 123
Pages: 787-792
Peer Reviewed
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