2010 Fiscal Year Final Research Report
Mechanisms of infection of Helicobacter pylori in human.
| Project/Area Number |
20590354
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Human pathology
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| Research Institution | Keio University |
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Principal Investigator |
YAMADA Taketo Keio University, 医学部, 准教授 (60230463)
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| Project Period (FY) |
2008 – 2010
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| Keywords | ピロリ菌 / パイエル板 / 胃炎 / 胃潰瘍 / リンパ腫 / 樹状細胞 |
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| Research Abstract |
Helicobacter pylori(HP) causes gastritis and gastric ulcer, and then induces gastric carcinoma and MALToma. We examined whether coccoid type HP was transmitted in Peyer patches. The localization of HP in Peyer patches of the infectee was detected as a spherical bacterial body. In the ITP and Sjogren's syndrome case, the bacterial body was not found. These results may indicate that Peyer patches is important in a gain of cellular immunity against HP and coccoid type HP may be done phagocytosis by dendritic cells in Peyer patches.
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Research Products
(8 results)
