2010 Fiscal Year Final Research Report
Clinicopathological features of malignant lymphoma in Japan : Miyagi Study
| Project/Area Number |
20590555
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Tohoku University |
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Principal Investigator |
ICHINOHASAMA Ryo Tohoku University, 大学院・医学系研究科, 教授 (30184625)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 臨床血液学 / 悪性リンパ腫 / 疫学 / 宮城県 / CD20 / BACH2 |
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| Research Abstract |
A total of 1,552 cases of newly diagnosed malignant lymphoma in Miyagi prefecture between 2002 and 2008 were enrolled in this epiemiological study. The rate of follicular lymphoma (24%) was higher than that in previous reports from Asian countries, and similar to that in Western countries. The analysis of each subtype of B-cell lymphoma revealed the incidence for lack of CD20 expression by either flow cytometry or immunohistochemistry (4% or 4%) and the discrepancy of CD20 expression between the results of flow-cytometry and immunohistochemistry (6.3%).
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