2012 Fiscal Year Final Research Report
Application of ischemia modified albumin as an indicator of hypoxia
| Project/Area Number |
20590585
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2008 – 2012
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| Keywords | IMA / アルブミン / 虚血 / 慢性呼吸不全 |
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| Research Abstract |
Ischemia-modified albumin (IMA) is produced inside human body especially peripheral tissue during ischemic damage. We hypothesized IMA could be an indicator of hypoxia to increase during progress of respiratory disease. Assaying serum IMA obtained from 12 respiratory patients, we could not detect significant difference. However, other markers such as paraoxonase1 and soluble receptor for advanced glycation end-product seemed to be candidates of tissue ischemia and atherosclerosis.
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