Association between dietary intake and serum composition of n-3 poly unsaturated fatty acids, and it’s influence on gender difference in atherosclerosis

2011 Fiscal Year Final Research Report

• Project/Area Number: 20590643
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Shiga University of Medical Science
• Principal Investigator: OKUDA Nagako 滋賀医科大学, 生活習慣病予防センター, 客員助教 (80452233)
• Co-Investigator(Kenkyū-buntansha): UESHIMA Hirotsugu 滋賀医科大学, 医学部, 特任教授 (70144483)
• Co-Investigator(Renkei-kenkyūsha): KITA Yoshikuni 滋賀医科大学, 医学部, 助教 (30147524)
• Project Period (FY): 2008 – 2011
• Keywords: 保健栄養 / 循環器疾患 / 脂質代謝

Research Abstract

Serum fatty acids compositions were measured to examine effect of gender difference in associations between dietary fatty acids intakes and serum lipids using blood samples of men and women living in Japan and Hawaii, obtained from international cooperative nutrition epidemiology study (INTERMAP). Possibility was indicated that being women, or under influence of female hormone, might be associated with less elevation of serum marine n-3 PUFA (i.e. EPA, DHA).

Research Products

• [Journal Article] INTERLIPID Research Group. Relation of dietary and lifestyle traits to difference in serum leptin of Japanese in Japan and Hawaii: the INTERLIPID study (2012)
  • Author(s): Nakamura Y, Ueshima H, Okuda N, Miura K, Kita Y, Okamura T, Turin TC, Okayama A, Rodriguez B, Curb JD, Stamler J
  • Journal Title: Nutr Metab Cardiovasc Dis Volume: 22(1) Pages: 14-22
  • Peer Reviewed
• [Journal Article] Relationship between Dietary and Other Lifestyle Habits and Cardiometabolic Risk Factors in Men (2011)
  • Author(s): Katano S, Nakamura Y, Okuda N, Murakami Y, Chiba N, Yoshita K, Tanaka T, Tamaki J, Takebayashi T, Okayama A, Miura K, Okamura T, Ueshima H
  • Journal Title: Diabetol Metab Syndr
  • Peer Reviewed
• [Journal Article] NIPPON DATA80/90 Research Group. Fatty acids intakes and serum lipid profiles: NIPPON DATA90 and the national nutrition monitoring (2010)
  • Author(s): Nakamura Y, Okuda N, Turin TC, Fujiyoshi A, Okamura T, Hayakawa T, Yoshita K, Miura K, Ueshima H
  • Journal Title: J Epidemiol Volume: 20 Suppl 3 Pages: S544-8
  • Peer Reviewed
• [Journal Article] Relationship of the polyunsaturated to saturated fatty acid ratio to cardiovascular risk factors and metabolic syndrome in Japanese: the INTERLIPID study (2010)
  • Author(s): Guo Z, Miura K, Turin TC, Hozawa A, Okuda N, Okamura T, Saitoh S, Sakata K, Nakagawa H, Okayama A, Yoshita K, Kadowaki T, Choudhury SR, Nakamura Y, Rodriguez BL, Curb DJ, Elliott P, Stamler J, Ueshima H
  • Journal Title: J Atheroscler Thromb Volume: 17(8) Pages: 777-784
  • Peer Reviewed
• [Journal Article] The INTERLIPID Study (2009)
  • Author(s): 奥田奈賀子
  • Journal Title: 血栓と循環 Volume: 17(2) Pages: 215-217
• [Journal Article] INTERLIPID Research Group. Relation of dietary and other lifestyle traits to difference in serum adiponectin concentration of Japanese in Japan and Hawaii: the INTERLIPID Study (2008)
  • Author(s): Nakamura Y, Ueshima H, Okuda N, Higashiyama A, Kita Y, Kadowaki T, Okamura T, Murakami Y, Okayama A, Choudhury SR, Rodriguez B, Curb JD, Stamler J
  • Journal Title: Am J Clin Nutr Volume: 88(2) Pages: 424-430
  • Peer Reviewed
• [Journal Article] 予防医学の視点からみた栄養の現状と対策の視点(健康日本21をふまえて) (2008)
  • Author(s): 奥田奈賀子、上島弘嗣
  • Journal Title: 栄養評価と治療 Volume: 25 Pages: 114-117
• [Journal Article] 日本人と脂質異常症の疫学コレステロール (2008)
  • Author(s): 奥田奈賀子、上島弘嗣
  • Journal Title: 臨床栄養 Volume: 113 Pages: 411-416
• [Presentation] 職域における食事性脂質改善に重点をおいた高LDLコレステロール血症保健指導の実践 (2010)
  • Author(s): 奥田奈賀子、原めぐみ、三浦克之、門田文、藤吉朗、村上義孝、清水満理子、舩越傳、上島弘嗣、岡村智教
  • Organizer: 第46回日本循環器病予防学会
  • Place of Presentation: 東京
  • Year and Date: 20100600
• [Presentation] 日本における多量飲酒者の栄養摂取の特徴 : INTERMAP Japan研究より (2009)
  • Author(s): 奥田奈賀子、三浦克之、Turin TC, 上島弘嗣、中川秀昭、中村幸志、由田克士、松村康弘、岡山明
  • Organizer: 第44回日本アルコール・薬物医学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 20090900
• [Presentation] Jeremiah Stamler for the INTERMAP Research Group．Dietary Factors Related to Higher Small LDL Particle Concentration of Japanese-American Men in Hawaii Compared with Japanese Men in Japan: The INTERLIPID Study (2009)
  • Author(s): Nagako Okuda, Katsuyuki Miura, Hirotsugu Ueshima, Akira Okayam, Shigeyuki Saitoh, Hideaki Nakagawa, Katshushi Yoshita, Kiyomi Sakata
  • Organizer: 49th Cardiovascular Disease Epidemiology and Prevention Annual Conference
  • Place of Presentation: 米国
  • Year and Date: 20090300