2010 Fiscal Year Final Research Report
Involvement of peritoneal macrophages and reactive mesothelial cells in pathological status of cirrhotic ascites
| Project/Area Number |
20590793
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Nara Medical University |
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Principal Investigator |
YAMAZAKI Masaharu Nara Medical University, 医学部, 講師 (60360054)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO Yasuyuki 奈良県立医科大学, 医学部, 教授 (70145879)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 肝硬変 / 腹水 |
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| Research Abstract |
In this study, we found that high VEGF-A concentration was observed in the medium in a co-culture of peritoneal macrophages and reactive mesothelial cells, which are major cellular components in ascites of cirrhotic patients. Moreover it was revealed that the ratio of peritoneal macrophages and reactive mesothelial cells could influence inflammatory cytokines profile in the culture medium.
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Research Products
(7 results)
