2010 Fiscal Year Final Research Report
Evaluation of effectiveness and safety of immune cell therapy for the unresectable locally advanced pancreatic cancer (Phase 2 trial)
| Project/Area Number |
20590806
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Gastroenterology
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
HIROOKA Yoshiki Nagoya University, 医学部附属病院, 准教授 (50324413)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
GOTO Hidemi 名古屋大学, 医学系研究科, 教授 (10215501)
ITOH Akihiro 名古屋大学, 医学系研究科, 講師 (30362239)
OHMIYA Nsoki 名古屋大学, 医学系研究科, 講師 (00335035)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 免疫細胞療法 / 切除不能局所進行膵癌 / 樹状細胞局注 |
|---|
| Research Abstract |
For the unresectable locally advanced pancreatic cancer, immune cell therapy was conducted. Immature dendritic cells were directly injected the target tumor using endoscopic ultrasonography guidance. Immature dendritic cell sensitized by tumor lysate grew up to the mature dendritic cell with tumor specific immunity and demonstrated tumor specific immunotoxicity to the human pancreatic cancer for the first time.
|
-
-
[Journal Article] A combination therapy of gemcitabine with immunotherapy for patients with inoperable locally advanced pancreatic cancer.2009
Author(s)
Hirooka Y, Itoh A, Kawashima H, Hara K, Nonogaki K, Kasugai T, Ohno E, Ishikawa T, Matsubara H, Ishigami M, Katano Y, Ohmiya N, Niwa Y, Yamamoto K, Kaneko T, Nieda M, Yokokawa K, Goto H.
-
Journal Title
Pancreas. 38
Pages: 69-74
Peer Reviewed
-
[Journal Article] Diagnosis of pancreatic disorders using contrast-enhanced endoscopic ultrasonography and endoscopic elastography.2009
Author(s)
Hirooka Y, Itoh A, Kawashima H, Ohno E, Ishikawa T, Matsubara H, Itoh Y, Nakamura M, Miyahara R, Ohmiya N, Niwa Y, Ishigami M, Katano Y, Goto H.
-
Journal Title
Clin Gastroenterol Hepatol. 7
Pages: 62-67
Peer Reviewed
-
-
-
-
-
-
