2010 Fiscal Year Final Research Report
Development of Three-dimensional Intravascular Ultrasound Imaging for Tissue Characterization of Coronary Plaques
| Project/Area Number |
20590822
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Gifu University |
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Principal Investigator |
KAWASAKI Masanori Gifu University, 医学部附属病院, 講師 (50214630)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 超音波 / 組織性状診断 / 後方散乱波 / 三次元画像 / 冠動脈 |
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| Research Abstract |
With the new system, we set 512 vector lines of ultrasound signal around the circumference, whereas 256 vector lines were used in the previous system. In addition, the sampling rate of ultrasound was improved from 100MHz to 320 and 400MHz.
We improved an online IB-IVUS imaging system for tissue characterization of coronary plaques. The use of the appropriate IB cutoff points for discriminating lipid pool, fibrosis and calcification resulted in tissue characterization with a high diagnostic accuracy. The thickness of fibrous cap measured by IB-IVUS was correlated with that measured by optical coherence tomography.
Quantitative tissue characterization of carotid plaques using IBS ultrasound was useful to predict newly appearing ipsilateral silent ischemic lesions after carotid artery stenting.
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[Journal Article] Evaluation of the Left Atrial Degeneration Using Integrated Backscatter Transesophageal Echocardiography for the Prediction of Atrial Fibrillation.2009
Author(s)
Kubota T, Kawasaki M, Takasugi N, Takeyama U, Ishihara Y, Okubo M, Yamaki T, Ojio S, Aoyama T, Arai M, Nishigaki K, Takemura G, Fujiwara H, Minatoguchi S
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Journal Title
JACC Cardiovasc Imaging 2
Pages: 1039-1047
Peer Reviewed
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[Journal Article] Development of Integrated Backscatter Intravascular Ultrasound for Tissue Characterization of Coronary Plaques.2008
Author(s)
Okubo M, Kawasaki M, Ishihara Y, Takeyama U, Kubota T, Yamaki T, Ojio S, Nishigaki K, Takemura G, Saio M, Takami T, Minatoguchi S, Fujiwara H.
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Journal Title
Ultrasound in Med Bird 34
Pages: 655-663
Peer Reviewed
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[Journal Article] Tissue Characterization of Coronary Plaques-Comparison of Integrated Backscatter Intravascular Ultrasound With Virtual Histology Intravascular Ultrasound-.2008
Author(s)
Okubo M, Kawasaki M, Ishihara Y, Takeyama U, Yasuda S, Kubota T, Tanaka S, Yamaki T, Ojio S, Nishigaki K, Takemura G, Saio M, Takami T, Fujiwara H, Minatoguchi S
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Journal Title
Cire J 72
Pages: 1631-1639
Peer Reviewed
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[Remarks] ホームページ等
