2010 Fiscal Year Final Research Report
The study of cancer treatment by regulating bone marrow-derived endothelial progenitor cells.
| Project/Area Number |
20590910
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
OHSAKI Yoshinobu Asahikawa Medical College, 医学部, 教授 (30191935)
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| Project Period (FY) |
2008 – 2010
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| Keywords | EPCs / PGI2-IP signaling / 肺癌 |
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| Research Abstract |
PGI2-IP signaling in EPCs is crucial for neovascularization, and plays an important role for tumor growth. PGI2-IP signaling in bone marrow-derived cells (BMDCs), including EPCs, participates in the process of the formation of lung tumor metastasis in lung very much. We showed the possibility of lung cancer treatment targeting PGI2-IP signaling.
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