2010 Fiscal Year Final Research Report
Roles of CLIP170 on glucose transport.
| Project/Area Number |
20591060
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Metabolomics
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| Research Institution | Yamaguchi University |
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Principal Investigator |
EMOTO Masahiro Yamaguchi University, 医学部, 准教授 (50294640)
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| Project Period (FY) |
2008 – 2010
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| Keywords | グルコース / 微小管 / 糖尿病 |
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| Research Abstract |
Insulin dependent glucose transport is one of the most important steps for insulin action in peripheral tissues. However, the precise mechanism how insulin regulates glucose transport is still unclear. In this project, CLIP170 was identified as a microtubule plus -end protein by MALDI-TOF MS analysis. This protein had a essential roles on GLUT4-vesicle translocation to the plasma membrane and glucose uptake in response to insulin stimulation.
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Research Products
(23 results)
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[Journal Article] Identification of Glypican3 as a novel GLUT4-binding protein.2008
Author(s)
Taguchi A, Emoto M, Okuya S, Fukuda N, Nakamori Y, Miyazaki M, Miyamoto S, anabe K, Aburatani H, Oka Y, Tanizawa Y.
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Journal Title
Biochem. Biophys. Res. Commun. 369
Pages: 1204-8
Peer Reviewed
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