2010 Fiscal Year Final Research Report
Contemporary reconsideration of bacterial infectious using pathological section : Verification of blind spot of bacteria test
| Project/Area Number |
20591210
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Infectious disease medicine
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| Research Institution | Fujita Health University |
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Principal Investigator |
SHIOGAMA Kazuya Fujita Health University, 医学部, 助教 (10387699)
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| Co-Investigator(Renkei-kenkyūsha) |
TSUTSUMI Yutaka 藤田保健衛生大学, 医学部, 教授 (80138643)
INADA Ken_ichi 藤田保健衛生大学, 医学部, 准教授 (70246081)
TERAMOTO Hidemi 藤田保健衛生大学, 医学部, 研究生 (80304236)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 細菌感染症 / 病理診断 / 免疫組織化学 / In situ hybridization法 |
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| Research Abstract |
We examined the situation of clinically undetected or overlooked bacterial infection caused by general bacteria from the viewpoint of pathological diagnosis. We created a bacterial colony sample panel and established histochemical detection conditions in the pathology sample. A specific positive signal could be detected in all examples except for E. coli. The result of clinical bacterial isolate and immunostaining in the pyuria cell block specimen was consistent in 10/12 examples. The in situ hybridization method was negative in all examples ; therefore it is necessary to consider changing to a probe with more efficient detection.
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Research Products
(20 results)
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[Journal Article] Locked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer development2009
Author(s)
Yamamichi N, Shimomura R, Inada K, Sakurai K, Haraguchi T, Ozaki Y, Fujita S, Mazutani T, Furukawa C, Fujishiro M, Ichinose M, Shiogama K, Tsutsumi Y, Omata M, Iba H
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Journal Title
Clin Cancer Res 15(12)
Pages: 4009-4016
Peer Reviewed
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