2010 Fiscal Year Final Research Report
A research of nutritional strategies to prevent metabolic syndrome in patients with fetal growth restriction
| Project/Area Number |
20591296
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Nagoya University |
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Principal Investigator |
HAYAKAWA Masahiro Nagoya University, 医学部附属病院, 講師 (40343206)
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| Co-Investigator(Kenkyū-buntansha) |
OKUMURA Akihisa 順天堂大学, 医学部, 准教授 (60303624)
SATO Yoshiaki 名古屋大学, 医学部附属病院, 助教 (30435862)
NAKAYAMA Atsushi 名古屋大学, 医学部附属病院, 助教 (30452197)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 胎児発育不全 / 中枢神経障害 / 栄養管理 / 合成トロンボキサンA2 |
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| Research Abstract |
Fetal growth restriction (FGR) is one of the causes of small-for-gestational age (SGA). SGA is high risk of neurological squelae in later life. Neonatologists have introduced aggressive nutrition to SGA infants in order to prevent from neurological sequelae. However, it is suggested that such nutritional strategies might produce metabolic syndrome in later life. In this study, postnatal nutritional intervention might induce metabolic syndrome in later life and alternation of lipid in brain. It is suggested that optimal nutritional strategies might be important in SGA infants in order to decrease morbidity.
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