• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2010 Fiscal Year Final Research Report

Redox regulating system and its application for neonatal chronic lung disease in mice

Research Project

  • PDF
Project/Area Number 20591311
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Embryonic/Neonatal medicine
Research InstitutionResearch Institute, Osaka Medical Center for Maternal and Child Health

Principal Investigator

YANAGIHARA Itaru  Research Institute, Osaka Medical Center for Maternal and Child Health (60314415)

Project Period (FY) 2008 – 2010
Keywords新生児慢性肺疾患
Research Abstract

Ureaplasma spp. is detected in the urogenital tract, including the vagina, cervix, chorioamnion, and placenta. Their colonization is associated with histologic chorioamnionitis (CAM). In this study, pathologic examinations of 151 placentas delivered at <32 wk of gestation were performed. Among 151 placentas, 42% (63/151) were culture positive for Ureaplasma spp. Colonization by Ureaplasma spp. was an independent risk factor for CAM (OR, 11.27 ; 95% CI, 5.09 -24.98).

  • Research Products

    (14 results)

All 2011 2010 2009 2008 Other

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (6 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.2011

    • Author(s)
      Yamashita K, Yanagihara I, Tsutsumi Y, et al.
    • Journal Title

      Nat Nanotechnol. 6(5)

      Pages: 321-8

    • Peer Reviewed
  • [Journal Article] Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin.2010

    • Author(s)
      Yanagihara I, Nakahira K, Honda T, et al.
    • Journal Title

      J Biol Chem. 285(21)

      Pages: 16267-74

    • Peer Reviewed
  • [Journal Article] Placental features of chorioamnionitis colonized with Ureaplasma species in preterm delivery.2010

    • Author(s)
      Namba F, Hasegawa T, Yanagihara I, et al.
    • Journal Title

      Pediatr Res. 67(2)

      Pages: 166-72

    • Peer Reviewed
  • [Journal Article] Birth length is a predictor of adiponectin levels in Japanese young children.2010

    • Author(s)
      Nishihara M, Yanagihara I, Waguri M, et al.
    • Journal Title

      J Pediatr Endocrinol Metab. 23

      Pages: 913-920

    • Peer Reviewed
  • [Journal Article] 胎内感染と流早産・新生児合併症2008

    • Author(s)
      柳原格、下屋浩一郎
    • Journal Title

      日本周産期・新生児医学会雑誌 44(4)

      Pages: 1032-3

  • [Journal Article] 妊婦及び早産児からのウレアプラズマ属細菌の分離培養2008

    • Author(s)
      柳原格
    • Journal Title

      日本産婦人科感染症研究会会誌 24

      Pages: 41-5

  • [Presentation] The pathological findings and molecular mechanisms of Ureaplasma spp. infection in preterm delivery2010

    • Author(s)
      柳原格
    • Organizer
      7^<th> European Society for Infectious Diseases in Obstetrics and Gynaecology (ESIDOG)
    • Place of Presentation
      Trieste, Italy, Invited
    • Year and Date
      20101002-20101005
  • [Presentation] ウレアプラズマ感染-流早産そして次世代への影響-2010

    • Author(s)
      柳原格
    • Organizer
      第37回日本マイコプラズマ学会
    • Place of Presentation
      東京、シンポジスト
    • Year and Date
      20100610-20100611
  • [Presentation] LPS誘導性早産モデルマウスに対するチオレドキシンの有効性2010

    • Author(s)
      柳原格
    • Organizer
      京都大学ウイルス研究所ミニシンポジウムレドックス生命医科学の展望(ATL Allergy TRX)
    • Place of Presentation
      京都、招待講演
    • Year and Date
      2010-03-15
  • [Presentation] Analysis of tetrameric structure of TDH2009

    • Author(s)
      Yanagihara I, Honda T, et al.
    • Organizer
      44^<th> US-Japan Cooperative Medical Science Program.
    • Place of Presentation
      San Diego, CA, USA, Invited
    • Year and Date
      20091117-20091119
  • [Presentation] 大阪府立母子保健総合医療センターにおける感染性早産制御に向けた試み2009

    • Author(s)
      柳原格、難波文彦、北島博之、中山雅弘、藤村正哲
    • Organizer
      第112回日本小児科学会
    • Place of Presentation
      奈良、オーラル
    • Year and Date
      20090417-20090419
  • [Presentation] WHO Preterm Birth International Collaborative Meeting.2008

    • Author(s)
      柳原格
    • Organizer
      Pathway Group
    • Place of Presentation
      Geneva, Switzerland, Invited
    • Year and Date
      20080421-20080423
  • [Remarks] ホームページ

    • URL

      http://www.med.osaka-u.ac.jp/pub/inst-mch/IM/mysite2/index.html

  • [Patent(Industrial Property Rights)] 母体投与用薬剤2008

    • Inventor(s)
      淀井淳司、三浦美樹子、柳原格、難波文彦、中平久美子
    • Industrial Property Rights Holder
      レドックスバイオサイエンス社、淀井淳司、三浦美樹子、柳原格、難波文彦、中平久美子
    • Industrial Property Number
      特許,特許出願2008-261081
    • Filing Date
      2008-10-07

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi