2010 Fiscal Year Final Research Report
The neural basis of delusional misidentification in dementia with Lewy bodies
| Project/Area Number |
20591413
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Kumamoto University |
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Principal Investigator |
HASHIMOTO Mamoru Kumamoto University, 医学部附属病院, 講師 (20452881)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Manabu 熊本大学, 生命科学研究部, 教授 (60284395)
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| Project Period (FY) |
2008 – 2010
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| Keywords | レビー小体型認知症 / 妄想 / 神経基盤 |
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| Research Abstract |
In dementia with Lewy bodies (DLB) the prevalence of delusion was higher than that in any other dementia. The principal component analysis for all kinds of delusion in DLB revealed that misidentificational delusion and contents specific delusion such as delusional theft or delusional jealousy might related reciprocally.Furthermore, Alzheimer's disease patients with subcortical ischemic vascular lesionswere significantly more delusional than those without. This result suggests thatsubcortical ischemic vascular lesions may be considered as a risk factor for thedevelopment of delusions in degenerative dementia.
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Research Products
(14 results)
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[Journal Article] Neuropsychiatric symptoms in patients with idiopathic normal pressure hydrocephalus.2009
Author(s)
Kito Y, Kazui H, Kubo Y, Yoshida T, Takaya M, Wada T, Nomura K, Hashimoto M, Ohkawa S, Miyake H, Ishikawa M, Takeda M.
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Journal Title
Behavioural Neurology 21
Pages: 165-174
Peer Reviewed
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