2010 Fiscal Year Final Research Report
Brain structural change in child and adolescent depression
| Project/Area Number |
20591423
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Nippon Medical School |
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Principal Investigator |
SAITO Takuya 日本医科大学, 医学部, 准教授 (20246961)
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| Co-Investigator(Kenkyū-buntansha) |
OKUBO Yoshiro 日本医科大学, 大学院・医学研究科, 教授 (20213663)
TATENO Amane 日本医科大学, 医学部, 講師 (50297917)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 児童精神医学 |
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| Research Abstract |
Depression is a major mental health problem in child and adolescent and the prevalence is estimated approximately 5-8% and is gradually increased. However, there is no biological maker for child and adolescent for diagnosis and treatment. To find association between biomarkers and symptoms for child depression is important. 8 major depressive disorder child and age matched non-depressive 7clinical samples are participated in an MRI experiment. Whole-brain analyses were conducted and the results of these analyses were examined for potential relationships with depression severity, Quality of life and General psychopathology.
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[Journal Article] Contribution of dopamine D1 and D2 receptors to amygdala activity in human2010
Author(s)
Takahashi H, Takano H, Kodaka F, Arakawa R, Yamada M, Otsuka T, Hirano Y, Kikyo H, Okubo Y, Kato M, Obata T, Ito H, Suhara T
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Journal Title
J Neurosci
Volume: 30(8)
Pages: 3043-7
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