2010 Fiscal Year Final Research Report
Analysis of articular cartilage in rheumatoid arthritis by 3-Tesla MRI
| Project/Area Number |
20591448
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagasaki University |
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Principal Investigator |
UETANI Masataka Nagasaki University, 大学院・医歯薬学総合研究科, 教授 (40176582)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAGUCHI Tetsuji 長崎大学, 病院, 助教 (30380893)
KAWAKAMI Atsushi 長崎大学, 大学院・医歯薬学総合研究科, 教授 (90325639)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 3テスラMRI / 関節軟骨 / T2 / 関節リウマチ / 変形性関節症 |
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| Research Abstract |
We evaluated the MR imaging technique and analyzing methods of articular cartilage of the knee. T2 values of the cartilage are different in parts of the joint without any morphological abnormalities. The cartilage damage is more frequent and T2 values are also higher in the medial compartment than other compartments of the asymptomatic knee. This variation should be considered in analyzing the cartilage damage in rheumatoid arthritis and T2 ratio is useful to analyze the cartilage in different parts of the knee.
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[Journal Article] Comparative study of the detection of joint injury in early-stage rheumatoid arthritis by MRI of wrist and finger joints and physical examination.2010
Author(s)
Tamai M, Kawakami A, Iwamoto N, Kawashiri SY, Fujikawa K, Aramaki T, Kita J, Okada A, Koga T, Arima K, Kamachi M, Yamasaki S, Nakamura H, Ida H, Origuchi T, Aoyagi K, Uetani M, Eguchi K
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Journal Title
Arthritis Care Res 36
Pages: 1126-1129
Peer Reviewed
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[Journal Article] High serum cartilage oligomeric matrix protein determines the subset of patients with early-stage rheumatoid arthritis with high serum C-reactive protein, matrix metalloproteinase-3, and MRI-proven bone erosion.2009
Author(s)
Fujikawa K, Kawakami A, Tamai M, Uetani M, Takao S, Arima K, Iwamoto N, Aramaki T, Kawashiri S, Ichinose K, Kamachi M, Nakamura H, Origuchi T, Ida H, Aoyagi K, Eguchi K
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Journal Title
J Rheumatol 36
Pages: 1126-1129
Peer Reviewed
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[Journal Article] A prediction rule for disease outcome in patients with undifferentiated arthritis using magnetic resonance imaging of the wrists and finger joints and serologic autoantibodies.2009
Author(s)
Tamai M, Kawakami A, Uetani M, Takao S, Arima K, Iwamoto N, Fujikawa K, Aramaki T, Kawashiri SY, Ichinose K, Kamachi M, Nakamura H, Origuchi T, Ida H, Aoyagi K, Eguchi K
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Journal Title
Arthritis Rheum 61
Pages: 772-778
Peer Reviewed
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[Presentation] MRI-proven bone edema of wrist and finger joints at entry is the strongest predictor toward further radiographic progression in patients with undifferentiated arthritis : results from the prospective cohort at Nagasaki University.2010
Author(s)
Kita J, Kawakami A, Tamai M, Iwamoto N, Kawashiri SY, Arima K, Okada A, Koga T, Yamasaki S, Nakamura H, Origuchi T, Aoyagi K, Uetani M, Eguchi K
Organizer
ACR/ARHP Annual Scientific Meeting
Year and Date
2010-11-07
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[Presentation] bone edema of wrist and finger joints at entry is the strongest predictor toward further radiographic progression in patients with undifferentiated arthritis : results from the prospective cohort at Nagasaki University.2010
Author(s)
Kita J, Tamai M, Iwamoto N. Kawashiri S, Kamachi M, Arima K, Okada A, Koga T. Yamasaki S, Nakamura H, Origuchi T, Ida H, Aoyagi K, Uetani M, Eguchi K, Kawakami A
Organizer
EULAR 2010, Rome
Year and Date
2010-06-16
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[Presentation] Evaluation of ACR/EULAR new rheumatoid arthritis criteria by nagasaki early arthritis cohort in japan : comparison with Nagasaki score for the RA development from undifferentiated arthritis.2010
Author(s)
Tamai M, Kawakami A, Arima K, Iwamoto N, Kita J, Kawashiri S, Kamachi M, Okada A, Koga T, Yamasaki S, Nakamura H, Origuchi T, Ida H, Uetani M, Aoyagi K, Eguchi K
Organizer
EULAR 2010, Rome
Year and Date
2010-06-16
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[Presentation] A Prediction Rule for Disease Outcome in Patients with Undifferentiated Arthritis by MRI of the Wrists and Finger Joints and Serologic Autoantibodies : Second Report Regarding to the Utility of Plain MRI.2009
Author(s)
Tamai M, Kawakami A, Uetani M, Arima S, Fujikawa K, Iwamoto T, Kawashiri S, Kita J, Koga T, Aramaki T, Kamachi M, Nakamura H, Ida H, Origuchi T, Aoyagi K, Eguchi K
Organizer
ACR/ARHP Annual Scientific Meeting
Place of Presentation
Philadelphia
Year and Date
2009-10-17
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[Presentation] Early Therapeutic Intervention Toward Patients in Undifferentiated Arthritis with MEI-Proven Bone Changes and Autoantibodies by Disease Modifying Anti-Rheumatic Drugs (DMARDS) : Nagasaki Early Arthritis lntervention Trial.2009
Author(s)
玉井慎美, 川上純, 上谷雅孝, 川尻真也, 岩本直樹, 藤川敬太, 荒牧俊幸, 蒲池誠, 有馬和彦, 中村英樹, 井田弘明, 折口智樹, 青柳潔, 江口勝美
Organizer
EULAR2009
Place of Presentation
Copenhagen
Year and Date
2009-06-10
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[Presentation] A Prediction Rule for Disease Outcome in Patients with Undifferentiated Arthritis Using MRI of Wrists and Finger Joints and Serologic Autoantibodies.2009
Author(s)
Tamai M, Kawakami A, Uetani M, Arima S, Fujikawa K, Iwamoto T, Kawashiri S, Kita J, Koga T, Aramaki T, Kamachi M, Nakamura H, Ida H, Origuchi T, Aoyagi K, Eguchi K
Organizer
EULAR 2009
Place of Presentation
Copenhagen
Year and Date
2009-06-10
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[Presentation] シンポジウム 画像診断2 早期関節リウマチにおける非造影手関節MRIの有用性の検討2009
Author(s)
玉井慎美, 川上純, 上谷雅孝, 有馬和彦, 岩本直樹, 藤川敬太, 山崎聡士, 川尻真也, 荒牧俊幸, 一瀬邦弘, 蒲池誠, 中村英樹, 井田弘明, 折口智樹, 青柳潔, 江口勝美
Organizer
第53回日本リウマチ学会総会・学術集会
Place of Presentation
東京
Year and Date
2009-04-23
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[Presentation] リウマチ診断学の進歩関節リウマチを早期に予測するには?2009
Author(s)
川上純, 玉井慎美, 岩本直樹, 川尻真也, 藤川敬太, 荒牧俊幸, 一瀬邦広, 有馬和彦, 蒲池誠, 中村英樹, 井田弘明, 折口智樹, 上谷雅孝, 青柳潔, 江口勝美
Organizer
第53回日本リウマチ学会総会・学術集会
Place of Presentation
東京
Year and Date
2009-04-23
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[Presentation] 診断未確定関節炎の評価2009
Author(s)
玉井慎美, 川上純, 上谷雅孝, 有馬和彦, 岩本直樹, 藤川敬太, 川尻真也, 荒牧俊幸, 一瀬邦弘, 蒲池誠, 山崎聡士, 中村英樹, 井田弘明, 折口智樹, 青柳潔, 江口勝美
Organizer
第53回日本リウマチ学会総会・学術集会
Place of Presentation
東京
Year and Date
2009-04-23
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[Presentation] 関節リウマチの予後改善のために抗CCP抗体と関節リウマチの診断・病態2008
Author(s)
川上純, 玉井慎美, 岩本直樹, 川尻真也, 藤川敬太, 荒牧俊幸, 一瀬邦広, 蒲池誠, 中村英樹, 井田弘明, 折口智樹, 上谷雅孝, 青柳潔, 江口勝美
Organizer
第52回日本リウマチ学会学術集会
Place of Presentation
札幌
Year and Date
2008-04-21
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[Presentation] 早期関節リウマチでの両手撮像MRI.2008
Author(s)
玉井慎美, 上谷雅孝, 川上純, 川尻真也, 岩本直樹, 藤川敬太, 荒牧俊幸, 一瀬邦弘, 蒲池誠, 有馬和彦, 中村英樹, 井田弘明, 折口智樹, 青柳潔, 江口勝美
Organizer
第52回日本リウマチ学会学術集会
Place of Presentation
札幌
Year and Date
2008-04-21
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