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2010 Fiscal Year Annual Research Report

X線による新しい分子イメージングの総合的研究

Research Project

Project/Area Number 20591460
Research InstitutionIwate Medical University

Principal Investigator

佐藤 英一  岩手医科大学, 共通教育センター, 教授 (90154038)

KeywordsX線CT / エネルギー弁別 / 分子イメージング / CdTe / LSO-MPPC / YAP(Ce)-MPPC / ZnO-MPPC / エンボス撮影
Research Abstract

振動式エネルギー弁別ライセンサーの開発
本研究では,CdTeセンサーを5.0~25.0mmlsの速度で振動させることによりプロジェクションデータを撮るためのラインセンサーを試作した。次いで,被写体を回転させながらプロジェクションデータを撮ることによりエネルギー弁別CT撮影を行った。
●高速エネルギー弁別X線センサーの開発
LSOおよびYAP(Ce)シンチレーターを1×1×1mmに成形し,マルチピクヤルフォトンカウンター(MPPC)の受光面直上に貼り付けた。X線フォトンの入射によりMPPCで発生する電荷を積分し増幅してイベントシグナルを得た。電荷有感型増幅噐と成形増幅果の時定数を短くし,最大で10Mcpsのカウントレートを達成した。
●振動式高速エネルギー弁別ラインセンサーの開発
上起の高速エネルギー弁別X線センサーを移動速度が600mmls程度の単軸ロボットに取り付けて振動式のラインセンサーを試作した。
●基礎研究用高速エネルギー弁別X線CTシステムの開発
上記の高速ラインセンサーを用い,ターンテーブル上に被写体を載せて回転することにより,高速エネルギー弁別撮影を行った。
●動物用高速エネルギー弁別X線CTシステムの開発
被写体を固定し,振動式センサーとX線源を一体化して回転させる方式のエネルギー弁別X線CTシステムを構築した。
●KエッジCT
振動式CdTeセンサー付きの基礎研究用エネルギー弁別CTを使ってヨウ素KエッジCT,セリウムKエッジCT,そしてガドリニウムKエッジCTを行った。
●高速KエッジCT
LSO-MPPCおよびLSO-YAP(Ce)センサー付きの高速エネルギー弁別CTを使って,ヨウ素KエッジCTとガドリニウムKエッジCTを行った。
●拡大エンボス撮影
空間分解能の向上を目的とし,100μmフォーカスX線装置を用いて被写体の3倍拡大撮影を行い,シングルエネルギーとデュアルエネルギーのエンボス撮影を行った。

  • Research Products

    (50 results)

All 2011 2010

All Journal Article (26 results) (of which Peer Reviewed: 26 results) Presentation (24 results)

  • [Journal Article] Demonstration of 10 keV-width K-edge Imaging Using an Energy-Discrimination X-ray Computed Tomography System Utilizinga Silicon-PIN Detector2011

    • Author(s)
      O.Hagiwara, M.Watanabe, E.Sato, H.Matsukiyo, A.Osawa, J.Nagao
    • Journal Title

      Med.Imag.Inform.Sci.

      Volume: SBN978-4-905149-01-9 Pages: 24-29

    • Peer Reviewed
  • [Journal Article] Conventional X-ray fluorescence camera with a cadmium-telluride detector and its application to cancer diagnosis2011

    • Author(s)
      T.Enomoto, E.Sato, P.Abderyim, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, M.Watanabe, J.Nagao, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.A

      Volume: 635 Pages: 108-115

    • Peer Reviewed
  • [Journal Article] First demonstration of 10 keV-width energy-discrimination K-edgeradiography using a cadmium-telluride X-ray camera with a tungsten-target tube2011

    • Author(s)
      M.Watanabe, E.Sato, P.Abderyim, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, T.Enomoto, J.Nagao, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.A

      Volume: 637 Pages: 171-177

    • Peer Reviewed
  • [Journal Article] Monochromatic flash embossed radiography using clean K photons from a spherical-plasma target2011

    • Author(s)
      A.Osawa, E.Sato, Y.Oda, A.Abudurexiti, P.Abderyim, O.Hagiwara, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.A

      Volume: 635 Pages: 131-136

    • Peer Reviewed
  • [Journal Article] Application of an oscillation-type linear cadmium telluride detector to enhanced gadolinium K-edge computed tomography2011

    • Author(s)
      H.Matsukiyo, E.Sato, O.Hagiwara, A.Abudurexiti, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.A

      Volume: 632 Pages: 142-146

    • Peer Reviewed
  • [Journal Article] First demonstration of iodine mapping in nonliving phantoms using an X-ray fluorescence computed tomography system with a cadmium telluride detector and a tungsten-target tube2011

    • Author(s)
      E.Sato, Y.Sato, S.Ehara, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.A

      Volume: 638 Pages: 187-191

    • Peer Reviewed
  • [Journal Article] Embossed radiography utilizing a subtraction-program in conjunction with a 0.5-mm-focus x-ray tube2010

    • Author(s)
      E.Sato, A.Purkhet, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, K.Takahashi, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Proc.SPIE

      Volume: 7622 Pages: 76222I(1-9)

    • Peer Reviewed
  • [Journal Article] Energy-discrimination x-ray computed tomography system utilizing a scanning cadmium-telluride detector2010

    • Author(s)
      E.Sato, A.Ablajan, T.Enomoto, M.Watanabe, K.Hitomi, K.Takahashi, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Proc.SPIE

      Volume: 7622 Pages: 76222Z(1-7)

    • Peer Reviewed
  • [Journal Article] Energy-discriminating Gadolinium K-edge X-ray computed tomography system2010

    • Author(s)
      H.Matsukiyo, M.Watanabe, E.Sato, A.Osawa, T.Enomoto, J.Nagao, P.Abderyim, K.Aizawa, K.Hitomi, E.Tanaka, H.Mori, T.Kawai, A.Ogawa, K.Takahashi, S.Sato, J.Onagawa
    • Journal Title

      Jpn.J.Appl.Phys.

      Volume: 49 Pages: 027001(1-6)

    • Peer Reviewed
  • [Journal Article] Magnification embossed radiography utilizing image-shifting subtraction program Jpn.J.Appl.Phys.2010

    • Author(s)
      A.Osawa, M.Watanabe, E.Sato, H.Matsukiyo, T.Enomoto, J.Nagao, P.Abderyim, K.Aizawa, E.Tanaka, H.Mori, T.Kawai, A.Ogawa, K.Takahashi, S.Sato, J.Onagawa
    • Journal Title

      Jpn.J.Appl.Phys.

      Volume: 49 Pages: 037001(1-7)

    • Peer Reviewed
  • [Journal Article] Embossed radiography utilizing an image-shifting subtraction program2010

    • Author(s)
      E.Sato, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, P.Abderyim, K.Takahashi, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.Phys.Res.A

      Volume: 619 Pages: 133-139

    • Peer Reviewed
  • [Journal Article] Energy-discrimination X-ray computed tomography system utilizing a cadmium telluride detector2010

    • Author(s)
      E.Sato, P.Abderyim, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, K.Hitomi, K.Takahashi, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Nucl.Instr.Meth.Phys.Res.A

      Volume: 619 Pages: 262-265

    • Peer Reviewed
  • [Journal Article] Demonstration of iodine K-edge imaging using an energy-discrimination X-ray computed tomography system with a cadmium telluride detector2010

    • Author(s)
      A.Abudurexiti, M.Kameda, E.Sato, P.Abderyim, T.Enomoto, M.Watanabe, K.Hitomi, E.Tanaka, H.Mori, T.Kawai, K.Takahashi, S.Sato, A.Ogawa, J.Onagawa
    • Journal Title

      Radiol.Phys.Technol.

      Volume: 3 Pages: 127-135

    • Peer Reviewed
  • [Journal Article] The excitation of harmonic X-rays by multiple excited electrons2010

    • Author(s)
      R.Germer, E.Sato
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: D02(1-6)

    • Peer Reviewed
  • [Journal Article] Second hard X-ray harmonic generation from linear ferrum-plasma target2010

    • Author(s)
      E.Sato, R.Germer, T.Enomoto, M.Watanabe, K.Sato, S.Sato, A.Ogawa, K.Takayama
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: D03(1-4)

    • Peer Reviewed
  • [Journal Article] High-speed photon-counting X-ray computed tomography system utilizing a zinc-oxide detector2010

    • Author(s)
      E.Sato, Y.Oda, T.Kawai, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: E02(1-5)

    • Peer Reviewed
  • [Journal Article] ZnO radiation sensors using a hydrothermally grown ZnO single crystal2010

    • Author(s)
      H.Endo, T.Chiba, K.Meguro, K.Takahashi, M.Fujisawa, S.Sugimura, S.Narita, E.Sato, Y.Kashiwaba
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: E03(1-6)

    • Peer Reviewed
  • [Journal Article] Optical properties of ZnO single crystals grown using hydrothermal process and ZnO/MPPC high-speed radiation sensors2010

    • Author(s)
      S.Sugimura, H.Endo, Y.Kashiwaba, E.Sato
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: E04(1-5)

    • Peer Reviewed
  • [Journal Article] High-count-rate X-ray computed tomography system utilizing anoscillation-type linear-YAP(Ce)detector2010

    • Author(s)
      Y.Oda, E.Sato, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: E05(1-5)

    • Peer Reviewed
  • [Journal Article] High-count-rate X-ray computed tomography system utilizing an LSO-MPPC detector2010

    • Author(s)
      E.Sato, Y.Oda, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: F01(1-4)

    • Peer Reviewed
  • [Journal Article] High-energy-resolution X-ray computed tomography system utilizing a silicon-PIN detector2010

    • Author(s)
      O.Hagiwara, E.Sato, Y.Oda, M.Sagae, A.Abudurexiti, P.Abderyim, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, K.Sato, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: F02(1-4)

    • Peer Reviewed
  • [Journal Article] Energy-discrimination X-ray fluorescence computed tomography system using a tungsten-target tube2010

    • Author(s)
      Y.Sato, E.Sato, S.Ehara, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: F03(1-4)

    • Peer Reviewed
  • [Journal Article] Flash embossed radiography using a weakly-ionized spherical-plasma X-ray generator2010

    • Author(s)
      A.Osawa, E.Sato, Y.Oda, A.Abudurexiti, P.Abderyim, O.Hagiwara, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: G01(1-5)

    • Peer Reviewed
  • [Journal Article] Energy-discrimination X-ray camera utilizing a cadmium telluride detector and a tungsten-target tube2010

    • Author(s)
      M.Watanabe, E.Sato, P.Abderyim, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, J.Nagao, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: G03(1-4)

    • Peer Reviewed
  • [Journal Article] Energy-discrimination gadolinium-K-edge computed tomography system using an oscillating linear-cadmium-telluride detector2010

    • Author(s)
      H.Matsukiyo, E.Sato, O.Hagiwara, M.Sagae, A.Abudurexiti, P.Abderyim, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, K.Sato, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: G04(1-4)

    • Peer Reviewed
  • [Journal Article] X-ray fluorescence camera with a cadmium-telluride detector and a tungsten tube2010

    • Author(s)
      T.Enomoto, E.Sato, P.Abderyim, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Journal Title

      Proc.ICHSIP-29

      Volume: SBN978-4-905149-01-9 Pages: G05(1-4)

    • Peer Reviewed
  • [Presentation] Mcps-range Photon-counting X-ray computed tomography system utilizing an LSO-MPPC sensor2011

    • Author(s)
      E.Sato, Y.Oda, A.Abudurexiti, O.Hagiwara, A.Osawa H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Saito A.Ogawa
    • Organizer
      2011 Int.Workshop Advanced Nanovisi on Science, Hamamatsu
    • Place of Presentation
      Hamamatsu(Invited paper)
    • Year and Date
      2011-07-17
  • [Presentation] 拡大エンボスX線撮影2010

    • Author(s)
      佐藤英一, 小田泰行, 大沢晃弘
    • Organizer
      日本生体医工学会東北支部大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-20
  • [Presentation] LSO-MPPC検出器を使ったフォトンカウンティングX線CTシステム2010

    • Author(s)
      佐藤英一, 小田泰行, 佐藤公悦
    • Organizer
      日本生体医工学会東北支部大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-20
  • [Presentation] 汎用蛍光X線カメラの開発と癌部位の観察2010

    • Author(s)
      佐藤英一, 萩原令彦, 佐藤公悦
    • Organizer
      日本生体医工学会東北支部大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-20
  • [Presentation] Embossed radiography utilizing a subtraction program in conjunction with a 0.5-mm-focus tube2010

    • Author(s)
      E.Sato, M. Sagae, A. Abudurexiti
    • Organizer
      10th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Taipei
    • Year and Date
      2010-10-17
  • [Presentation] Energy-discrimination x-ray computed tomography system utilizing a cadmium telluride detector2010

    • Author(s)
      E.Sato, Y.Oda, A. Abudurexiti
    • Organizer
      10th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Taipei
    • Year and Date
      2010-10-16
  • [Presentation] Photon-counting x-ray computed tomography system utilizing an oscillating linear-YAP(Ce) photon sensor2010

    • Author(s)
      A. Abudurexiti, Y.Oda, E.Sato, M. Kameda
    • Organizer
      10th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Taipei
    • Year and Date
      2010-10-16
  • [Presentation] Optical properties of ZnO single crystals grown using hydrothermal process and ZnO/MPPC high-speed radiation sensors2010

    • Author(s)
      S.Sugimura, H.Endo, Y.Kashiwaba, E.Sato
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-22
  • [Presentation] ZnO sensors and their applications2010

    • Author(s)
      H.Endo, T.Chiba, K.Meguro, K.Takahashi, M.Fujisawa, S.Sugimura, S.Narita, E.Sato, Y.Kashiwaba
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka(Invited paper)
    • Year and Date
      2010-09-22
  • [Presentation] High-energy-resolution X-ray computed tomography system utilizing a silicon-PIN detector2010

    • Author(s)
      O.Hagiwara, E.Sato, Y.Oda, M.Sagae, A.Abudurexiti, P.Abderyim, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, K.Sato, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-22
  • [Presentation] Gadolinium K-edge computed tomography system utilizing an oscillating linear cadmium-telluride detector2010

    • Author(s)
      H.Matsukiyo, E.Sato, O.Hagiwara, M.Sagae, A.Abudurexiti, P.Abderyim, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, K.Sato, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-22
  • [Presentation] High-speed photon counting using a ZnO-MPPC module and its application to an X-ray computed tomography system2010

    • Author(s)
      E.Sato, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-22
  • [Presentation] Irradiation of harmonic X-rays from linear ferrum-plasma target2010

    • Author(s)
      E.Sato, R.Germer, T.Enomoto, M.Watanabe, K.Sato, S.Sato, A.Ogawa, K.Takayama
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka(Invited paper)
    • Year and Date
      2010-09-22
  • [Presentation] 10-Mcps photon-counting X-ray computed tomography system utilizing a LSO-MPPC sensor2010

    • Author(s)
      E.Sato, Y.Oda, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka(Invited paper)
    • Year and Date
      2010-09-22
  • [Presentation] X-ray fluorescence camera utilizing a cerium X-ray generator2010

    • Author(s)
      T.Enomoto, E.Sato, P.Abderyim, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-21
  • [Presentation] Conventional X-ray fluorescence computed tomography system utilizing a cadmium-telluride detector2010

    • Author(s)
      Y.Sato, S.Ehara, E.Sato, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-21
  • [Presentation] Molecular-level X-ray imaging utilizing a cadmium telluride detector2010

    • Author(s)
      M.Watanabe, E.Sato, P.Abderyem, A.Abudurexiti, O.Hagiwara, H.Matsukiyo, A.Osawa, J.Nagao, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka(Invited paper)
    • Year and Date
      2010-09-21
  • [Presentation] High-spatial-resolution embossed radiography2010

    • Author(s)
      A.Osawa, E.Sato, A.Abudurexiti, P.Abderyem, O.Hagiwara, H.Matsukiyo, T.Enomoto, M.Watanabe, Jiro Nagao, Shigehiro Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka(Invited paper)
    • Year and Date
      2010-09-21
  • [Presentation] High-speed embossed radiography utilizing a pulsed X-ray generator and a computed radiography system2010

    • Author(s)
      A.Osawa, E.Sato, A.Abudurexiti, P.Abderyim, O.Hagiwara, H.Matsukiyo, T.Enomoto, M.Watanabe, J.Nagao, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-21
  • [Presentation] High-speed photon-counting X-ray computed tomography system utilizing an oscillating linear-YAP(Ce) photon sensor2010

    • Author(s)
      Y.Oda, E.Sato, A.Abudurexiti, O.Hagiwara, A.Osawa, H.Matsumoto, T.Enomoto, M.Watanabe, J.Nagao, S.Sugimura, H.Endo, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-20
  • [Presentation] Energy-discrimination X-ray camera utilizing a cerium X-ray generator2010

    • Author(s)
      E.Sato, P.Abderyim, T.Enomoto, M.Watanabe, K.Sato, S.Sato, A.Ogawa
    • Organizer
      29th Int.Congress High-Speed Imaging and Photonics
    • Place of Presentation
      Morioka
    • Year and Date
      2010-09-20
  • [Presentation] 拡大エンボスX線撮影2010

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    • Organizer
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    • Place of Presentation
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    • Organizer
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    • Place of Presentation
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    • Year and Date
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    • Organizer
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    • Place of Presentation
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    • Year and Date
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Published: 2012-07-19  

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