2010 Fiscal Year Final Research Report
Function of New vascular endothelial growth factor (EG-VEGF) in colon cancer.
| Project/Area Number |
20591587
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | University of Fukui |
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Principal Investigator |
YAMAGUCHI Akio University of Fukui, 医学部附属病院, 教授 (10174608)
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| Co-Investigator(Kenkyū-buntansha) |
GOI Takanori 福井大学, 医学部附属病院, 講師 (60225638)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 大腸癌 / 血管新生因子 / 浸潤 / 転移 |
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| Research Abstract |
To improve the prognosis of cancer patients, it is essential to inhibit the capacity of cancer cells for hematogenous metastasis as well as their proliferative capacity. EG-VEGF factor enhances the angiogenesis and cell invasion in colon cancer. EG-VEGF antibody that we established, inhibibites the angiogenesis and cell inavasion in colon cancer. EG-VEGF molecule-targeted therapy has the potential for improving survival rates.
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