2010 Fiscal Year Final Research Report
Epidermal cooling for spinal cord protection against ischemia
| Project/Area Number |
20591641
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
TABAYASHI Koichi Tohoku University, 大学院・医学系・研究科, 名誉教授 (90142942)
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| Co-Investigator(Kenkyū-buntansha) |
SAIKI Yoshikatsu 東北大学, 大学院・医学系研究科, 教授 (50372298)
KAWAMOTO Shunsuke 東北大学, 大学院・医学系研究科, 准教授 (20400244)
MOTOYOSHI Naotaka 東北大学, 病院, 講師 (40375093)
MARUYAMA Shigenao 東北大学, 流体科学研究所, 教授 (80173962)
KOMIYA Atsuki 東北大学, 流体科学研究所, 助教 (60371142)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 心臓大血管外科学 / 神経保護 / 脊髄保護 / 局所冷却 |
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| Research Abstract |
Epidermal cooling may bring protective effect against ischemia on deep tissue such as spinal cord which can be suffered from ischemia during clinical thoracoabdominal aortic repair. Computed simulation model on deep tissue temperature change by epidermal cooling has been established by the experimental evaluations both on animal and human models. However, clinical application was not accepted because the preliminary study showed that mild frostbite occurred on normal tissue after epidermal cooling.
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