2010 Fiscal Year Final Research Report
The absorbable process of bioengineered graft assessed by in vivo imaging
| Project/Area Number |
20591644
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
KOTANI Junichi Osaka University, 心臓血管内科, 医長 (10448029)
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| Co-Investigator(Kenkyū-buntansha) |
SAITO Mitsuhiro 大阪大学, 医学部付属病院, 特任助教 (20448038)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 血管内イメージング / 循環器 / 自己組織化グラフト |
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| Research Abstract |
The potent mechanism of bioabsorbable graft was considered two ways : contact between blood cells and luminal surface, and contact between adventitia and neighbor tissue. These were assessed by color, smoothing of the surface, and neovascularization outside the graft. The findings were observed by intravascular ultrasound, optical coherence tomography and angioscopy ; those are used in clinical. Serial observation using imaging modality in vivo may become a new methodology instead of patho-histological assessment after scarified animal.
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