2010 Fiscal Year Final Research Report
Fragility fractures in frail elderly-elucidation of the mechanism and a development of the prevention
| Project/Area Number |
20591778
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tottori University |
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Principal Investigator |
HAGINO Hiroshi Tottori University, 医学部, 教授 (80208412)
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| Research Collaborator |
HAYASHIBARA Masako 鳥取大学, 医学部, 大学院博士課程
SHIMA Takayuki 鳥取大学, 医学部, 大学院博士課程
MATSUMOTO Hiromi 鳥取大学, 医学部, 大学院後期博士課程
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| Project Period (FY) |
2008 – 2010
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| Keywords | 骨・軟骨代謝学 / 高齢者骨折 / 転倒 / 関節リウマチ |
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| Research Abstract |
Fall incidence was 50% per year in women with rheumatoid arthritis and drug use and balance impairment were significant risk factors of falls. Imbalance of lower leg muscle was observed in patients with osteoarthritis who fell. In arthritis animal model osteogenic factor was reduced by arthritis responding to the mechanical loading. The incidence of subsequent fractures was 6.2% for 1 year in patients with first hip fracture and low body mass index was associated with second fractures.
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