2010 Fiscal Year Final Research Report
Is angiogenesis in regenerative medicine influenced by anesthetics and perioperative management methods?
| Project/Area Number |
20591833
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | The University of Tokushima |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KITAHATA Hiroshi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (60161486)
OSHITA Shuzo 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (60144945)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 再生医療 / 血管新生 / 麻酔薬 / 周術期管理法 / 薬剤反応性 |
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| Research Abstract |
We examined the influence of various anesthetics on angiogenesis in animal experiments, clinical studies, and basic experiments using cultured cells. Animal experiments and clinical studies revealed the effect on angiogenesis of the inhalation anesthetic should be less, and basic experiments using cultured cells indicated part of the intravenous anesthetic tended to promote angiogenesis. It is hoped that a new indicator of the perioperative administration is established by the influence of the anesthetic which gives it to angiogenesis being elucidated.
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