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2010 Fiscal Year Final Research Report

Tumor-specific vaccine therapy using the epitope peptide derived from a tumor antigen gene for the upper urinary tract cancer

Research Project

  • PDF
Project/Area Number 20591864
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionIwate Medical University

Principal Investigator

FUJIOKA Tomoaki  Iwate Medical University, 医学部, 教授 (80173409)

Project Period (FY) 2008 – 2010
Keywords上部尿路上皮癌 / 腫瘍特異的 / ペプチドワクチン / 個別化医療
Research Abstract

We were stage and grade-independent, and novel tumor antigen MPHOSPH1 and DEPDC1 protein high frequently expressed in the upper urinary tract cancer with stage and grade-independent. The peptide vaccine treatmnet for the upper urinary tract cancer is safe and is useful as postoperative prevention of recurrence. TIL is involved in the antitumor effect.

  • Research Products

    (5 results)

All 2010 2009 2008 Other

All Journal Article (1 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.2010

    • Author(s)
      Harada Y, Kanehira M, Fujisawa Y, Takata R, Shuin T, Miki T, Fujioka T, Nakamura Y, Katagiri T
    • Journal Title

      Cancer Res 70

      Pages: 5829-39

  • [Book] がんペプチドワクチン療法(中村祐輔編)腎がん新規腫瘍抗原(HIG2)を利用したワクチン療法2009

    • Author(s)
      小原航、高田亮、藤岡知昭
    • Publisher
      中山書店
  • [Book] がんペプチドワクチン療法(中村祐輔編)膀胱がん新規腫瘍抗原(MPHOSPH1, DEPDC1)を利用したワクチン療法2009

    • Author(s)
      小原航、高田亮、兼平貢、藤岡知昭
    • Publisher
      中山書店
  • [Book] 【尿路上皮癌の診断と治療Update】膀胱癌組織の遺伝子発現解析によるMVACネオアジュバント化学療法の効果予測2008

    • Author(s)
      高田亮, 片桐豊雅, 兼平貢, 小原航, 中村祐輔, 藤岡知昭
    • Publisher
      Urology View
  • [Remarks] ホームページ等

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Published: 2012-01-26   Modified: 2016-04-21  

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