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2010 Fiscal Year Final Research Report

Basic research on the auto-transplantation of cryopresedved ovarian tissue - Aiming at the quality of life improvement of the young woman cancer patient.

Research Project

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Project/Area Number 20591933
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionSt.Marianna University School of Medicine

Principal Investigator

SUZUKI Nao  St.Marianna University School of Medicine, 医学部, 准教授 (90246356)

Co-Investigator(Kenkyū-buntansha) ISHIZUKA Bunpei  聖マリアンナ医科大学, 医学部, 教授 (80097336)
Project Period (FY) 2008 – 2010
Keywords卵巣組織凍結 / 若年女性癌患者 / ガラス化法 / カニクイザル / 自家移植
Research Abstract

As for this study, the accomplishment of the study of the basics that intended the quality of life improvement as the woman after the treatment remission of the young woman cancer patient becomes the whole design. We established the new technology regarding the auto-transplantation of cryopreserved ovarian tissue ; the optimal method of cryopreservation and the appropriate site of auto-transplantation. Finally we succeeded to get the fertilized egg from the auto transplant part of the cryopreserved ovary (vitrification) organization in the primate for the first time in the world.

  • Research Products

    (15 results)

All 2010 2009 2008 Other

All Journal Article (7 results) (of which Peer Reviewed: 3 results) Presentation (6 results) Book (1 results) Remarks (1 results)

  • [Journal Article] 若年女性に対する卵巣組織凍結・自家移植の現状とその実際~最新の情報2010

    • Author(s)
      鈴木直、橋本周、五十嵐豪、高江正道、杉下陽堂、奥津由記、細井美彦、森本義晴、石塚文平
    • Journal Title

      産婦人科の実際 59

      Pages: 1243-1249

  • [Journal Article] Cryopreservation of ovarian tissue was possible after pre-treatment with a gonadotropin-releasing hormone agonist.2010

    • Author(s)
      Igarashi S, Suzuki N, Osada M, Takae S, Tarumi W, Ishizuka B
    • Journal Title

      Reproductive Medicine and Biology 9

      Pages: 197-203.S

    • Peer Reviewed
  • [Journal Article] 特集産婦人科診療~pros and cons~生殖細胞保存の有用性-妊孕性の温存を目的とした生殖細胞の超急速凍結保存-2010

    • Author(s)
      橋本周、鈴木直、石塚文平、森本義晴
    • Journal Title

      産婦人科の実際 59

      Pages: 367-374

  • [Journal Article] Heterotopic auto-transplantation of ovarian cortex in cynomolgus monkeys.2010

    • Author(s)
      Igarashi S, Suzuki N, Hashimoto S, Takae S, Takenoshita M, Hosoi Y, Morimoto Y, Ishizuka B.
    • Journal Title

      Human Cell 3

      Pages: 26-34

    • Peer Reviewed
  • [Journal Article] 卵巣凍結保存・自家移植の現状2009

    • Author(s)
      鈴木直、高江正道、五十嵐豪、杉下陽堂、奥津由記、石塚文平
    • Journal Title

      臨床婦人科産科 63

      Pages: 1373-1377

  • [Journal Article] 特集妊孕能温存の婦人科がん治療がん化学療法と卵巣組織凍結-最近の話題-2009

    • Author(s)
      鈴木直、五十嵐豪、高江正道、石塚文平
    • Journal Title

      産婦人科の実際 58

      Pages: 309-315

  • [Journal Article] 抗がん剤による化学療法が若年女性癌患者の妊孕性に及ぼす影響2009

    • Author(s)
      鈴木直、石塚文平
    • Journal Title

      脳神経外科ジャーナル 18

      Pages: 361-366

    • Peer Reviewed
  • [Presentation] 【シンポジウム】ARTにおける技術革新:若年女性に対する卵巣組織凍結の現状2010

    • Author(s)
      鈴木直、石塚文平
    • Organizer
      第13回日本IVF学会
    • Place of Presentation
      大阪府(グランキューブ大阪(大阪国際会議場))
    • Year and Date
      2010-09-17
  • [Presentation] 【シンポジウム】卵子、卵巣凍結保存の現状と展望:若年婦人患者のQOL向上を目指した卵巣組織凍結・自家移植-基礎から臨床へ2010

    • Author(s)
      鈴木直、石塚文平
    • Organizer
      第28回日本受精着床学会総会・学術講演会
    • Place of Presentation
      神奈川県(パシフィコ横浜)
    • Year and Date
      2010-07-29
  • [Presentation] 【Selected Oral Presentation】Fertilized-ova from vitrified ovarian grafts in monkeys undergoing heterotopic autotransplantation : Development of a new vitrification technique.2010

    • Author(s)
      Suzuki N, Hashimoto S, Igarashi T, Takae S, Tsuji Y, Yamanaka M, Ohta S, Yamochi T, Takenoshita M, Hosoi Y, Morimoto Y, Ishizuka B.
    • Organizer
      The 26th Annual Meeting of European Society of Human Reproduction and Embryo-logy 2010
    • Place of Presentation
      Italy
    • Year and Date
      2010-06-29
  • [Presentation] 【Selected Oral Presentation】Heterotopic autotranplantation of ovarian cortex in cynomolgus monkeys.2009

    • Author(s)
      Suzuki N, Hashimoto S, Igarashi, Takae S, Tsuji Y, Ohta S, Yamochi T, Takenoshita M, Hosoi Y, Morimoto Y, Ishizuka B.
    • Organizer
      World Congress on Fertility Preservation
    • Place of Presentation
      Belgium
    • Year and Date
      2009-12-12
  • [Presentation] 【プレナリーセッション、招請講演】挙児希望女性のoligodendrogliomaの術後化学療法:抗がん剤による化学療法が若年女性がん患者の妊孕性に及ぼう影響2008

    • Author(s)
      鈴木直、石塚文平
    • Organizer
      第28回日本脳神経外科コングレス総会
    • Place of Presentation
      神奈川県(パシフィコ横浜)
    • Year and Date
      2008-05-11
  • [Presentation] カニクイザルを用いた卵巣組織自家移植に関する基礎的研究-若年女性がん患者のQOL向上を志向して2008

    • Author(s)
      鈴木直、橋本周、五十嵐豪、井埜まり絵、高江正道、辻陽子、木口一成、細井美彦、森本義晴、石塚文平
    • Organizer
      第60回日本産科婦人科学会総会・学術講演会
    • Place of Presentation
      神奈川県(パシフィコ横浜)
    • Year and Date
      2008-04-13
  • [Book] カラーアトラス不妊診療のための卵子学(鈴木秋悦編)(卵巣組織凍結保存法の現状)2009

    • Author(s)
      鈴木直、橋本周、細井美彦、森本義晴、石塚文平
    • Total Pages
      161-167
    • Publisher
      医歯薬出版、東京
  • [Remarks] 鈴木直、石塚文平.効くNews Specialヨーロッパ生殖医学会発不妊治療の最前線レポート 卵巣凍結法による妊娠力温存に注目集まる、日経ヘルス、P.58-59、2010.9

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Published: 2012-01-26   Modified: 2016-04-21  

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