2010 Fiscal Year Final Research Report
Uterine leiomyoma and metabolic syndrome-a new therapeutic strategy
| Project/Area Number |
20591945
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Tohoku University |
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Principal Investigator |
TAKEDA Takashi Tohoku University, 大学院・医学系・研究科, 准教授 (20301260)
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| Project Period (FY) |
2008 – 2010
|
| Keywords | 子宮筋腫 / メタボリックシンドローム / アンジオテンシン / アルドステロン / アディポネクチン / クルクミン / 移植モデル |
|---|
| Research Abstract |
We have shown that Ang II and aldosterone could potentiate the proliferation of leiomyoma cells. We have further shown that adiponectin, genistein and curcumin repressed the proliferation of leiomyoma cells. We have also established a novel xenograft model for uterine leiomyoma.
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Research Products
(14 results)
