2010 Fiscal Year Final Research Report
Analysis of the eustachian tubal cell secretion in the cell culture and its clinical aspects
| Project/Area Number |
20591968
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tohoku University |
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Principal Investigator |
OSHIMA Takeshi Tohoku University, 大学院・医学系・研究科, 准教授 (40241608)
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| Co-Investigator(Kenkyū-buntansha) |
KAWASE Tetsuaki 東北大学, 大学院・医工学研究科, 教授 (50169728)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 耳管開放症 / 鼻すすり / 耳管機能 |
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| Research Abstract |
The eustachian tube function was evaluated quantitatively in the rat, and then tubal opening and closing pressure was decreased by postural change and starvation. Primary cell culture of tubal epithelial and gland cells was attempted to examine the effect of the tubal mucosal secretion to the tubal function. Clinically, nasal instillation of saline was shown to be effective to patulous eustachian tube. Its mechanism is considered to be mechanical tubal closure and possible modulation of tubal secretion.
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Research Products
(13 results)
