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2010 Fiscal Year Final Research Report

細胞外マトリックスによる難聴に関する基礎的、臨床的研究

Research Project

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Project/Area Number 20591977
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionShinshu University

Principal Investigator

TAKUMI Yutaka  Shinshu University, 医学部, 准教授 (70312501)

Co-Investigator(Renkei-kenkyūsha) USAMI Shinichi  信州大学, 医学部, 教授 (10184996)
SUZUKI Nobuyoshi  信州大学, 医学部附属病院, 助教 (20377641)
HASHIMOTO Shigenari  信州大学, 医学部・附属病院, 助教(特定雇用) (90359729)
NISHIO Shinya  信州大学, 医学部, 研究員 (70467166)
Project Period (FY) 2008 – 2010
Keywords耳科学 / 細胞外マトリクス / 難聴遺伝子 / 蓋膜 / 血管条 / ラセン靭帯
Research Abstract

In Extra cellular matrix, many kind of collagen are contained and some species of them are reported as a responsible gene for deafness causing. In this study, we analyzed all kinds of collagen genes expression levels of inner ear and whole body. As a result, 13 collagen gene expressed twice or more in inner ear than whole body, And 6 collagen gene expressed 10 fold or more. These genes might be good candidates for new deafness causing genes.

  • Research Products

    (1 results)

All 2010

All Presentation (1 results)

  • [Presentation] 内耳におけるコラーゲン遺伝子バリアントのプロファイリング2010

    • Author(s)
      菊池安剛、鈴木伸嘉、橋本繁成、工穣、宇佐美真一
    • Organizer
      第20回日本耳科学会総会・学術講演会
    • Year and Date
      2010-10-07

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Published: 2012-01-26   Modified: 2016-04-21  

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